Lack of a Gonadal or Adrenal Androgenic Mechanism for the Hypertrichosis Produced by Diazoxide, Phenytoin, and Minoxidil

    May 1982 in “ Biochemical Pharmacology ”
    Lawrence N. Parker, Eric Lifrak, William D. Odell
    Image of study
    TLDR These drugs cause hair growth without affecting testosterone or adrenal hormones.
    The study found that the drugs diazoxide, phenytoin, and minoxidil do not stimulate testosterone secretion or adrenal androgen secretion, suggesting that the hypertrichosis induced by these drugs may be accomplished by a non-androgenic mechanism. However, the reason why the three drugs occasionally stimulate profuse hair growth is not clear.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 13 results

      community Medications that cause extra hair growth

      in Research/Science  123 upvotes 2 years ago
      The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.

      community Is this Better Than Topical Minoxidil? Topical Diazoxide

      in Research/Science  6 upvotes 6 months ago
      Topical diazoxide may be a promising hair regrowth treatment, especially for those who don't respond to minoxidil, as it activates potassium channels without needing sulfation. It appears safe for topical use, avoiding systemic effects seen in oral use.

      community Creatine is the opposite of minoxidil !

      in Research/Science  319 upvotes 1 week ago
      Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.

      community P-1075: a BETTER version of Minoxidil

      in Research/Science 2 weeks ago
      P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

    Related Research

    1 / 1 results