Lack of a Gonadal or Adrenal Androgenic Mechanism for the Hypertrichosis Produced by Diazoxide, Phenytoin, and Minoxidil

May 1982 in “ Biochemical Pharmacology ”

Lawrence N. Parker, Eric Lifrak, William D. Odell

diazoxide phenytoin minoxidil hypertrichosis testosterone adrenal androgen Rogaine

TLDR These drugs cause hair growth without affecting testosterone or adrenal hormones.

The study found that the drugs diazoxide, phenytoin, and minoxidil do not stimulate testosterone secretion or adrenal androgen secretion, suggesting that the hypertrichosis induced by these drugs may be accomplished by a non-androgenic mechanism. However, the reason why the three drugs occasionally stimulate profuse hair growth is not clear.

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research Lack of a Gonadal or Adrenal Androgenic Mechanism for the Hypertrichosis Produced by Diazoxide, Phenytoin, and Minoxidil

24 citations, May 1982 in “Biochemical Pharmacology”

These drugs cause hair growth without affecting testosterone or adrenal hormones.