Increased Vibrissa Growth in Transgenic Mice Expressing Insulin-Like Growth Factor 1

    February 1999 in “ ˜The œjournal of investigative dermatology/Journal of investigative dermatology ”
    Hexiu Su, Jonathan G. H. Hickford, Pauline H.B. The … Chris Frampton
    Studysummary In this study, researchers found that overexpression of IGF-1 in transgenic mice stimulated increased vibrissa growth during the first neonatal hair cycle compared to their nontransgenic littermates.
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    Research cited in this study 3

    1. Overexpression of Insulin-Like Growth Factor-1 Induces Hyperplasia, Dermal Abnormalities, and Spontaneous Tumor Formation in Transgenic Mice Oncogene · 1997
    2. The Insulin-Like Growth Factor 1 Receptor Is Expressed by Epithelial Cells with Proliferative Potential in Human Epidermis and Skin Appendages: Correlation of Increased Expression with Epidermal Hyperplasia Journal of Investigative Dermatology · 1996
    3. Hair-Specific Expression of Chloramphenicol Acetyltransferase in Transgenic Mice Under the Control of an Ultra-High-Sulfur Keratin Promoter Proceedings of the National Academy of Sciences · 1990