Hair Growth Promoting Activity of Discarded Biocomposite Keratin Extract

    Rashedunnabi Akanda, Hee Young Kim, Soo‐Jin Park, In‐Shik Kim, Dongchoon Ahn, Hyun‐Jin Tae, Byung‐Yong Park
    Image of study
    TLDR Keratin extract from human hair was found to promote hair growth in mice.
    The 2017 study demonstrated that keratin extract (KE) derived from discarded human hair promotes hair growth in C57BL/6 mice. The topical application of KE induced the anagen phase of hair follicles, increased the number and shaft of hair follicles, and expanded the deep subcutis area. KE was found to be biocompatible, with over 90% cell viability in human keratinocyte cells. It also upregulated the expression of growth factors and proteins such as FGF-10, VEGF, IGF-I, ß-catenin, and Shh, which are crucial for hair follicle development. The study concluded that KE could be a promising treatment for hair follicle disorders. The in vivo portion of the study involved 48 mice, divided into two groups, while the in vitro tests used HaCaT cells with KE concentrations of 25, 50, and 100 µg/ml.
    Discuss this study in the Community →

    Research cited in this study

    20 / 20 results

    Related Community Posts Join

    6 / 101 results

      community Fucking hell rosemary how is that possible

      in Chat  19 upvotes 2 years ago
      User reported hair regrowth and thicker hair after using rosemary oil, zinc, biotin, vitamin D, and a better diet. They believe rosemary oil contributed the most to the improvement.

      community Natural Remedies: Polyphenols and Hair Loss

       19 upvotes 5 years ago
      Natural remedies to treat hair loss, such as polyphenols, apple peel extract, grape seed extract, green tea extract, peppermint oil, pumpkin seed oil, apigenin, Ginkgo biloba, red clover extract, olive leaf extract, Ecklonia Cava and Grateloupia elliptica. In addition, terpenes, carotenoids, and tocopherols were discussed as potential treatments.

      community Results of Procyanidin B2 in clinical studies

      in Treatment  13 upvotes 4 years ago
      Procyanidin B2, a compound derived from Annurca apples, as a potential treatment for pattern hair loss. Several clinical studies were mentioned, which found that procyanidin B2 could increase hair growth, density, and keratin content. Other treatments such as Minoxidil, Finasteride, and RU58841 were not discussed.

      community This serum outperformed Minoxidil in a recent study. Please debunk

       23 upvotes 5 years ago
      A topical solution called "Multi-Peptide Serum for Hair Density" by The Ordinary Company, which contains several ingredients that are used in alternatives to Minoxidil and was found to have better results than 5% Minoxidil in a study. People who have tried it shared their experiences with the serum as well.

    Related Research

    2 / 2 results