The Use of Keratin Biomaterials Derived from Human Hair for the Promotion of Rapid Regeneration of Peripheral Nerves

    October 2007 in “ Biomaterials
    Paulina Sierpinski, Jeffrey P. Garrett, Jun Ma, Peter J. Apel, David C. Klorig, Thomas L. Smith, L. Andrew Koman, Anthony Atala, Mark Van Dyke
    TLDR Keratin from human hair helps nerves heal faster.
    The study explored the use of keratin biomaterials derived from human hair to promote peripheral nerve regeneration. Researchers extracted keratins from human hair and formed hydrogels with interconnected pores, which were tested for their ability to support Schwann cell migration, proliferation, and gene expression. The keratin hydrogels demonstrated favorable properties for cell penetration and tissue remodeling, suggesting that they could serve as a neuroinductive provisional matrix. This approach showed potential for improving functional recovery in nerve injuries, potentially surpassing the limitations of traditional nerve autografts.
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