TLDR Human hair growth and structure are influenced by keratin proteins, genes, melanin, and lipids.
The document explored various aspects of human hair formation and structure, focusing on the keratinization processes of epidermal keratinocytes and the histochemistry of hair follicles. It examined the role of keratin proteins and their genes in influencing hair growth, structure, and properties. The study also detailed the morphology and histochemistry of human hair, including the structural features and spatial arrangements of protein chains in hair and epidermal keratin intermediate filaments. Additionally, it discussed the factors affecting hair color, such as hair melanin, and analyzed the integral lipids of hair and the stratum corneum, as well as the sulfur amino acid composition of hair.
62 citations
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January 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.
100 citations
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December 2002 in “Journal of biological chemistry/The Journal of biological chemistry” Researchers mapped and categorized specific keratin-associated protein genes on human chromosome 21q22.1.
48 citations
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November 2002 in “Journal of biological chemistry/The Journal of biological chemistry” Genetic variations in hair keratin proteins exist but don't significantly affect hair structure.
272 citations
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September 2001 in “Journal of Biological Chemistry” Human hair keratins were cataloged, showing their roles in hair differentiation stages.
98 citations
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June 2001 in “Journal of biological chemistry/The Journal of biological chemistry” A cluster of sulfur-rich hair protein genes was found on chromosome 17.
77 citations
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March 2000 in “Journal of Investigative Dermatology” 235 citations
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July 1999 in “Journal of biological chemistry/The Journal of biological chemistry” Human hair is made up of different keratins, some strong and some weak, with specific types appearing at various stages of hair growth.
228 citations
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January 1997 in “Birkhäuser Basel eBooks” Keratin proteins and their genes are crucial for hair growth and structure.
48 citations
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair growth is controlled by specific gene clusters and proteins, and cysteine affects hair gene expression in sheep.
76 citations
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February 1993 in “Journal of Biological Chemistry” KAP6 genes are conserved across species and active in hair follicles.