The Role of Keratin Proteins and Their Genes in the Growth, Structure, and Properties of Hair

    January 1997 in “ Birkhäuser Basel eBooks ”
    Barry C. Powell, G.E. Rogers
    Studysummary This article integrates existing literature on hair follicle structure and formation at the cellular and molecular level, reporting no new findings.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 85

    1. A Sensitive Assay for the Enzyme Activity in Hair Follicles and Epidermis That Catalyzes the Peptidyl-Arginine-Citrulline Post-Translational Modification Current problems in dermatology · 2015
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    3. Targeted Expression of SV40 T Antigen in the Hair Follicle of Transgenic Mice Produces an Aberrant Hair Phenotype Journal of cell science · 1995
    4. Differential Expression of Genes Encoding a Cysteine-Rich Keratin Family in the Hair Cuticle Journal of Investigative Dermatology · 1994
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    6. Ultrastructural Visualization of Cross-Linked Protein Features in Epidermal Appendages Journal of Cell Science · 1994
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    12. Formation of Surface Membranes in Developing Mammalian Hair Fibers Micron · 1994
    13. Cells Within the Bulge Region of Mouse Hair Follicle Transiently Proliferate During Early Anagen: Heterogeneity and Functional Differences of Various Hair Cycles Differentiation · 1994
    14. Human Hair Keratins Journal of Investigative Dermatology · 1993
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    17. Organization and Expression of Hair Follicle Genes ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993
    18. Probing Keratinocyte and Differentiation Specificity of the Human K5 Promoter In Vitro and in Transgenic Mice Molecular and Cellular Biology · 1993
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    20. The Structure of Human Trichohyalin: Potential Multiple Roles as a Functional EF-Hand-Like Calcium-Binding Protein, a Cornified Cell Envelope Precursor, and an Intermediate Filament-Associated (Cross-Linking) Protein Journal of Biological Chemistry · 1993
    21. Skin-Specific Expression of a Truncated E1a Oncoprotein Binding to p105-Rb Leads to Abnormal Hair Follicle Maturation Without Increased Epidermal Proliferation The Journal of Cell Biology · 1993
    22. Analysis of the Sheep Trichohyalin Gene: Potential Structural and Calcium-Binding Roles of Trichohyalin in the Hair Follicle The Journal of Cell Biology · 1993
    23. Mouse Notch: Expression in Hair Follicles Correlates with Cell Fate Determination ˜The œjournal of cell biology/˜The œJournal of cell biology · 1993
    24. Fibroblast Growth Factor Influences the Development and Cycling of Murine Hair Follicles Developmental Biology · 1993
    25. Mice With a Null Mutation of the TGFα Gene Have Abnormal Skin Architecture, Wavy Hair, and Curly Whiskers and Often Develop Corneal Inflammation Cell · 1993
    26. Targeting Expression of Keratinocyte Growth Factor to Keratinocytes Elicits Striking Changes in Epithelial Differentiation in Transgenic Mice The EMBO Journal · 1993
    27. Sequence, Expression, and Evolutionary Conservation of a Gene Encoding a Glycine/Tyrosine-Rich Keratin-Associated Protein of Hair Journal of Biological Chemistry · 1993
    28. Human Trichohyalin Gene Is Clustered with the Genes for Other Epidermal Structural Proteins and Calcium-Binding Proteins at Chromosomal Locus 1q21 Journal of Investigative Dermatology · 1993
    29. Complete Sequence of a Hair-Like Intermediate Filament Type II Keratin Gene DNA sequence · 1993
    30. Structural Features and Sites of Expression of a New Murine 65 kD and 48 kD Hair-Related Keratin Pair, Associated with a Special Type of Parakeratotic Epithelial Differentiation Differentiation · 1992
    31. Cachexia and Graft-Versus-Host Disease-Type Skin Changes in Keratin Promoter-Driven TNF Alpha Transgenic Mice Genes & Development · 1992
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    33. Trichohyalin: Purification from Porcine Tongue Epithelium and Characterization of the Native Protein Journal of Investigative Dermatology · 1992
    34. Hair Follicle Differentiation: Expression, Structure, and Evolutionary Conservation of the Hair Type II Keratin Intermediate Filament Gene Family Development · 1992
    35. Structure and Site of Expression of a Murine Type II Hair Keratin Molecular Biology Reports · 1992
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    37. Localization of Epidermal Growth Factor Immunoreactivity in Sheep Skin During Wool Follicle Development Journal of Investigative Dermatology · 1992
    38. Chromosomal Localization of Mouse Hair Keratin Genes Annals of the New York Academy of Sciences · 1991
    39. Regulation of Keratin Gene Expression in Hair Follicle Differentiation Annals of the New York Academy of Sciences · 1991
    40. Hair-Specific Keratins: Characterization and Expression of a Mouse Type I Keratin Gene Journal of Investigative Dermatology · 1991
    41. Transient Expression of Mouse Hair Keratins in Transfected HeLa Cells: Interactions Between Hard and Soft Keratins Journal of Investigative Dermatology · 1991
    42. The Presence of Glycoproteins in the Cell Membrane Complex of Various Keratin Fibers Biochimica et Biophysica Acta (BBA) - General Subjects · 1991
    43. Transgenic Mice Provide New Insights Into the Role of TGF-Alpha During Epidermal Development and Differentiation Genes & Development · 1991
    44. Expression of Calcyclin, a Calcium-Binding Protein, in the Keratogenous Region of Growing Hair Follicles Journal of Investigative Dermatology · 1991
    45. Patterns of Epithelial Expression of Fos Protein Suggest Important Role in the Transition from Viable to Cornified Cell During Keratinization Development · 1991
    46. An Ultrahigh-Sulphur Keratin Gene of the Human Hair Cuticle Is Located at 11q13 and Cross-Hybridizes with Sequences at 11p15 Mammalian Genome · 1991
    47. Structure and Biochemistry of Mammalian Hard Keratin Electron Microscopy Reviews · 1991
    48. Serine-Rich Ultra High Sulfur Protein Gene Expression in Murine Hair and Skin During the Hair Cycle Journal of Biological Chemistry · 1990
    49. Structure and Expression of Genes for a Class of Cysteine-Rich Proteins of the Cuticle Layers of Differentiating Wool and Hair Follicles ˜The œjournal of cell biology/˜The œJournal of cell biology · 1990
    50. Human Hair Growth In Vitro Journal of Cell Science · 1990
    51. Hair-Specific Expression of Chloramphenicol Acetyltransferase in Transgenic Mice Under the Control of an Ultra-High-Sulfur Keratin Promoter Proceedings of the National Academy of Sciences · 1990
    52. Cyclic Hair Loss and Regrowth in Transgenic Mice Overexpressing an Intermediate Filament Gene The EMBO Journal · 1990
    53. Differential Expression of Type I Hair Keratins Journal of Investigative Dermatology · 1990
    54. The cDNA-Deduced Amino Acid Sequence for Trichohyalin, a Differentiation Marker in the Hair Follicle, Contains a 23 Amino Acid Repeat ˜The œjournal of cell biology/˜The œJournal of cell biology · 1990
    55. Expression of Keratin K14 in the Epidermis and Hair Follicle: Insights Into Complex Programs of Differentiation The Journal of Cell Biology · 1989
    56. A Family of Type I Keratin Genes and the Homeobox-2 Gene Complex Are Closely Linked to the Rex Locus on Mouse Chromosome 11 Genomics · 1989
    57. An Ultra-High Sulfur Keratin Gene Is Expressed Specifically During Hair Growth Journal of Investigative Dermatology · 1989
    58. A New Look Into an Old Problem: Keratins as Tools to Investigate Determination, Morphogenesis, and Differentiation in Skin Genes & Development · 1989
    59. High-Sulfur Protein Deficient Human Hair: Clinical Aspects and Biochemical Study of Two Unreported Cases of a Variant Type of Trichothiodystrophy 1989
    60. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues Differentiation · 1988
    61. Cloning And Characterization Of A Mouse Type I Hair Keratin cDNA Journal of Investigative Dermatology · 1988
    62. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues II: Concomitant and Mutually Exclusive Synthesis of Trichocytic and Epithelial Cytokeratins in Diverse Human and Bovine Tissues (Hair Follicle, Nail Bed and Matrix, Lingual Papilla, Thymic Reticulum) Differentiation · 1988
    63. Concerted Gene Duplications in the Two Keratin Gene Families Journal of Molecular Evolution · 1988
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    65. A Group of Type I Keratin Genes on Human Chromosome 17: Characterization and Expression Molecular and Cellular Biology · 1988
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    71. Comparison of Epidermal Growth Factor Binding and Receptor Distribution in Normal Human Epidermis and Epidermal Appendages Journal of Investigative Dermatology · 1984
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    76. Structural Features of the Alpha-Type Filaments of the Inner Root Sheath Cells of the Guinea Pig Hair Follicle Biochemistry · 1978
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    78. The Histology of Keratin Fibers 1977
    79. Loss of a Homologous Group of Proteins in a Dominantly Inherited Ectodermal Malformation Biochemical Journal · 1976
    80. The Occurrence of the ε-(γ-Glutamyl)Lysine Cross-Link in the Medulla of Hair and Quill Biochimica et Biophysica Acta (BBA) - Protein Structure · 1972
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    82. The Localization And Significance Of Arginine And Citrulline In Proteins Of The Hair Follicle Journal of Histochemistry & Cytochemistry · 1963
    83. Newer Findings on the Enzymes and Proteins of Hair Follicles Annals of the New York Academy of Sciences · 1959
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    Related research 6

    1. Functional Analysis of Keratin Components in the Mouse Hair Follicle Inner Root Sheath British Journal of Dermatology · 2004
    2. Contrasting Localization of c-Myc with Other Myc Superfamily Transcription Factors in the Human Hair Follicle and During the Hair Growth Cycle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2001
    3. Expression of E6 and E7 Papillomavirus Oncogenes in the Outer Root Sheath of Hair Follicles Extends the Growth Phase and Bypasses Resting at Telogen PubMed · 2000
    4. Effects of Epidermal Growth Factor on the Morphology and Patterns of DNA Synthesis in Isolated Human Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1994
    5. Keratins of the Human Hair Follicle: Hyperproliferative Keratins Consistently Expressed in Outer Root Sheath Cells In Vivo and In Vitro Differentiation · 1987
    6. Outer Root Sheath Keratinization in Anagen and Catagen of the Mammalian Hair Follicle: A Seventh Distinct Type of Keratinization in the Hair Follicle - Trichilemmal Keratinization PubMed · 1981