Mice With a Null Mutation of the TGFα Gene Have Abnormal Skin Architecture, Wavy Hair, and Curly Whiskers and Often Develop Corneal Inflammation

    April 1993 in “ Cell ”
    G. Bruce Mann, Kerry J. Fowler, Anastasia Gabriel … Ashley R. Dunn
    Studysummary This study found that mice with a disrupted TGFα gene display a curly whisker-coat phenotype, similar to waved-1 mice, suggesting TGFα's crucial role in skin architecture and hair development.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on cell.com →
    Discuss this study in the Community →

    Research cited in this study 3

    1. The Secret Life of the Hair Follicle Trends in genetics · 1992
    2. Transgenic Mice Provide New Insights Into the Role of TGF-Alpha During Epidermal Development and Differentiation Genes & Development · 1991
    3. Distribution and Number of Epidermal Growth Factor Receptors in Skin Is Related to Epithelial Cell Growth Developmental Biology · 1983