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research Mice with a null mutation of the TGFα gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation

578 citations , April 1993 in “Cell”

This study found that mice with a disrupted TGFα gene display a curly whisker-coat phenotype, similar to waved-1 mice, suggesting TGFα's crucial role in skin architecture and hair development.

research Whisker hair--an update.

6 citations , June 1981 in “PubMed”

This article reviews previously reported cases of whisker hair in individuals who develop severe androgenic alopecia and offers a hypothesis concerning its eventual fate, without presenting new findings.

research Homozygous K5Cre transgenic mice have wavy hair and accelerated malignant progression in a murine model of skin carcinogenesis

7 citations , September 2006 in “Molecular Carcinogenesis”

This study observed that K5Cre +/+ transgenic mice develop a distinct phenotype characterized by wavy hair, curly whiskers, and an increased rate of papilloma malignant transformation.

research Expression of a dominant negative mutant of epidermal growth factor receptor in the epidermis of transgenic mice elicits striking alterations in hair follicle development and skin structure.

252 citations , November 1995 in “The EMBO Journal”

Blocking EGFR in mice causes hair loss and skin changes.

research Activation of the Notch pathway in the hair cortex leads to aberrant differentiation of the adjacent hair-shaft layers

109 citations , June 2000 in “Development”

This study reports that activating Notch signaling in the hair follicle cortex of transgenic mice caused abnormal differentiation of the medulla and cuticle, highlighting potential cell-cell interactions.

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community A less common type of hairloss case

5 upvotes 5 months ago

High-dose Lysine and Histidine supplements caused curly/kinky hair and shedding due to Elastin dysfunction. Minoxidil, white tea, and dark grape juice were mentioned as treatments to inhibit Elastase and mimic Lysyl Oxidase.

community DUPA / APHK discussion ( Diffuse unpatterned alopecia / Acquired Progressive Hair Kinkering )

4 upvotes 7 years ago

The user discusses their experience with diffuse unpatterned alopecia and acquired progressive hair kinkering, noting improvements with treatments including biotin, pantothenic acid, finasteride, ketoconazole, and zinc pyrithione shampoo. They report thicker, healthier hair and improved scalp condition, attributing success mainly to biotin, pantothenic acid, and finasteride.

community Did anybody not care at all about their hair until they started losing it?

in Chat 134 upvotes 1 year ago

People regret neglecting their hair until it started thinning, and they are now using treatments like finasteride, minoxidil, and microneedling. Some are considering stronger options like dutasteride due to mixed results.

community Curly hair advice on transplant

4 upvotes 1 month ago

The conversation discusses whether curly hair affects hair transplant outcomes, with advice to consult a specialist experienced with curly hair. The donor area's suitability is questioned, noting curly hair might appear thicker.

community CURLY HAIR HELP: Some questions about scalp buildup from topical minox

2 upvotes 1 year ago

The conversation discusses hair loss treatments, including finasteride, Nizoral shampoo, peppermint/castor oil with saw palmetto, and plans to start oral minoxidil. The user seeks advice on managing scalp buildup and flakiness from topical minoxidil, especially for curly hair, and considers using both oral and topical minoxidil.

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learn Curry leaf

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