Protein and Amino Acid Composition of Hair from Mice Carrying the Naked (N) Gene

The study compared the protein and amino acid compositions of hair from mice with the naked (N) gene to wild-type mice. It found that N/+ mice had similar protein spot positions to wild-type mice but reduced high tyrosine (HT) protein. N/N mice had fewer and possibly different protein spots, with less high-sulphur (HS) and HT protein content. Amino acid analysis showed that N/N hair had less half-cystine and tyrosine but higher levels of proline, threonine, and glycine, suggesting unusual protein components. The study concluded that the N gene indirectly influenced the synthesis of structural proteins in mouse hair.