Wool Keratin-Associated Protein Genes in Sheep: A Review

The review discussed significant progress in understanding wool keratin-associated proteins (KAPs) in sheep, which are crucial for wool fiber structure. Advances in sequencing allowed for the categorization of KAPs into families, identification of gene polymorphisms, and understanding of their chromosomal locations and gene expression characteristics. Genetic variation in KAP genes was linked to wool traits, offering potential for selective breeding to enhance wool quality. The review highlighted the complexity of KAPs, noting that 27 different KAP family members had been identified, though further research was needed to confirm these findings and explore unidentified ovine KAP genes.