Size Polymorphisms in the Human Ultrahigh Sulfur Hair Keratin-Associated Protein 4, KAP4, Gene Family

June 2005 in “ The journal of investigative dermatology/Journal of investigative dermatology ”

Naoyuki Kariya, Yutaka Shimomura, Masaaki Ito

keratin-associated protein 4 KAP4 hair fiber structure chromosome 17q12-21 cysteine-rich repeat segments polymorphic alleles PCR amplification nucleotide sequences bacterial artificial chromosome clone AC100808 keratin hair structure chromosome 17 cysteine repeats polymorphisms PCR BAC clone

Studysummary This study identified numerous size polymorphisms in the human ultrahigh sulfur KAP4 genes due to intragenic sequence variations, suggesting these polymorphisms may have arisen through deletions and duplications during evolution.

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