Identification of Two Novel Clusters of Ultrahigh-Sulfur Keratin-Associated Protein Genes on Human Chromosome 11

    Shoichi Yahagi, Kazunori Shibuya, Izumi Obayashi … Nobuyoshi Shimizu
    Studysummary In this study, two novel clusters of keratin-associated protein genes on human chromosome 11 were analyzed, suggesting their products are crucial for hair formation due to preferential expression in hair roots.
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    Research cited in this study 16

    1. A Cluster of 21 Keratin-Associated Protein Genes Within Introns of Another Gene on Human Chromosome 21q22.3 Genomics · 2004
    2. Hair Keratin Associated Proteins: Characterization of a Second High Sulfur KAP Gene Domain on Human Chromosome 21 in Fond Memory of Dr. Peter Steinert ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004
    3. Characterization of a First Domain of Human High Glycine-Tyrosine and High Sulfur Keratin-Associated Protein Genes on Chromosome 21q22.1 Journal of biological chemistry/˜The œJournal of biological chemistry · 2002
    4. Polymorphisms in the Human High Sulfur Hair Keratin-Associated Protein 1, KAP1, Gene Family Journal of biological chemistry/˜The œJournal of biological chemistry · 2002
    5. The Catalog of Human Hair Keratins Journal of Biological Chemistry · 2001
    6. Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-Associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21 Journal of biological chemistry/˜The œJournal of biological chemistry · 2001
    7. Characterization of a 300 Kbp Region of Human DNA Containing the Type II Hair Keratin Gene Domain Journal of Investigative Dermatology · 2000
    8. Pmg-1 and Pmg-2 Constitute a Novel Family of KAP Genes Differentially Expressed During Skin and Mammary Gland Development Mechanisms of Development · 1999
    9. Characterization of a 190-Kilobase Pair Domain of Human Type I Hair Keratin Genes Journal of biological chemistry/˜The œJournal of biological chemistry · 1998
    10. Formation and Structure of Human Hair Birkhäuser Basel eBooks · 1995
    11. Differential Expression of Genes Encoding a Cysteine-Rich Keratin Family in the Hair Cuticle Journal of Investigative Dermatology · 1994
    12. Isolation and Characterization of a Novel Hair Follicle-Specific Gene, Hacl-1 Journal of Investigative Dermatology · 1994
    13. Regulation of Keratin Gene Expression in Hair Follicle Differentiation Annals of the New York Academy of Sciences · 1991
    14. An Ultrahigh-Sulphur Keratin Gene of the Human Hair Cuticle Is Located at 11q13 and Cross-Hybridizes with Sequences at 11p15 Mammalian Genome · 1991
    15. Structure and Expression of Genes for a Class of Cysteine-Rich Proteins of the Cuticle Layers of Differentiating Wool and Hair Follicles ˜The œjournal of cell biology/˜The œJournal of cell biology · 1990
    16. Trichothiodystrophy: An Ultrastructural Study of the Hair Follicle British Journal of Dermatology · 1985