Skin-Specific Expression of a Truncated E1a Oncoprotein Binding to p105-Rb Leads to Abnormal Hair Follicle Maturation Without Increased Epidermal Proliferation

    June 1993 in “ The Journal of Cell Biology ”
    Caterina Missero, Carlos Serra, Kurt S. Stenn, G. Paolo Dotto
    Studysummary This study found that transgenic mice expressing a mutant E1a oncoprotein in their skin had disturbed hair follicle maturation but did not show increased tumor development or proliferation.
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    Research cited in this study 5

    1. Transgenic Mice Provide New Insights Into the Role of TGF-Alpha During Epidermal Development and Differentiation Genes & Development · 1991
    2. Patterns of Epithelial Expression of Fos Protein Suggest Important Role in the Transition from Viable to Cornified Cell During Keratinization Development · 1991
    3. Cyclic Hair Loss and Regrowth in Transgenic Mice Overexpressing an Intermediate Filament Gene The EMBO Journal · 1990
    4. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues: Human and Bovine Hair Follicles Differentiation · 1988
    5. The Dermal Papilla and Maintenance of Hair Growth 1988

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