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Glossary Skin Surface

outermost layer of skin acting as a protective barrier

The skin surface refers to the outermost layer of the skin, known as the epidermis. It acts as a protective barrier against environmental factors, such as pathogens and UV radiation, and plays a crucial role in regulating moisture and temperature. For professionals, understanding the skin surface is essential for diagnosing and treating various dermatological conditions, including alopecia, which can be influenced by the health and integrity of this layer.

Related Terms

Research

5 / 1000+ results

research Surface Lipids as Multifunctional Mediators of Skin Responses to Environmental Stimuli

105 citations , January 2010 in “Mediators of Inflammation”

This article reviews the role of skin surface lipid in mediating environmental stressors and discusses potential therapeutic interventions, reporting no new experimental findings.

research Microbial Biosurfactant as an Alternate to Chemical Surfactants for Application in Cosmetics Industries in Personal and Skin Care Products: A Critical Review

11 citations , January 2023 in “BioMed Research International”

This review discusses the use of microbial biosurfactants as a safer alternative to chemical surfactants in cosmetics due to their antibacterial, moisturizing, and low toxicity properties, but it reports no new clinical findings.

research Non-invasive human skin transcriptome analysis using mRNA in skin surface lipids

10 citations , March 2022 in “Communications biology”

In this study, researchers found that non-invasive analysis of skin surface lipid RNAs revealed alterations in gene expression patterns associated with atopic dermatitis, suggesting its potential for understanding skin disease pathophysiology.

research Non-invasive human skin transcriptome analysis using mRNA in skin surface lipids

2 citations , April 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study found that skin surface lipids contain measurable mRNAs, providing a non-invasive way to study skin diseases, with specific gene expression changes observed in atopic dermatitis patients.

research Evaluation of Residual Antibacterial Effects on Canine Skin Surface and Hairs Following Treatment with Five Commercial Mousse Products Against Staphylococcus pseudintermedius in vitro

July 2022

In this study, researchers found that topical mousse treatments containing chlorhexidine and other active ingredients showed significant antibacterial effects on both skin and hair in short-haired dogs, but mainly on hair in long-haired dogs, suggesting hair evaluations might overestimate skin-level efficacy.

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Community Join

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community New study suggests hair regrowth on wounded and bald skin may be possible

4 upvotes 7 years ago

Hair regrowth on wounded and bald skin may be possible by activating the sonic hedgehog gene, leading to hair regrowth in mice. The findings are promising but may not directly apply to humans.

community So does oral minoxidil age your skin or not

43 upvotes 2 years ago

Oral minoxidil may cause dry skin and dark eye bags but doesn't significantly age the skin. Topical minoxidil is toxic to cats, and some users prefer finasteride.

community Topical Finasteride that doesn’t go systematic is the cure

3 upvotes 1 year ago

Topical finasteride that doesn't penetrate the skin could potentially treat hair loss without side effects. Current challenges include finding a formulation that remains on the scalp without increasing blood levels.

community PP405 is NOT gray market jxl069

in Technology 26 upvotes 8 months ago

PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

community Finasteride and “anti-aging” effects

in Treatment 218 upvotes 1 year ago

Finasteride may help users look younger by suppressing DHT, affecting skin and hair. Users also emphasize skincare, sunscreen, and lifestyle for maintaining a youthful appearance.

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Learn

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learn Scalp Micropigmentation

How long does scalp micropigmentation take to heal? Providers say the skin surface usually heals in about 7-14 days, and some say full healing and pigment settling take 4-6 weeks.
Is scalp micropigmentation suitable for people with sensitive skin? Providers say scalp micropigmentation suits most skin types and describe patch tests, hypoallergenic pigments and a skin consultation for sensitive skin. These are provider claims rather than independent safety evidence, and pigment reactions remain a risk.

learn Stem Cell Factor

learn Neem Oil

Oil from the neem tree, used in traditional remedies

learn Melatonin

Can melatonin cause side effects on the skin or hair? No study links melatonin to hair loss; reports are anecdotal. Some users report scalp dryness or irritation from topical products, and a safety review lists mainly mild side effects such as sleepiness and headache.

learn Follistatin

Can follistatin be applied to the skin, and does any form of it treat hair loss? No study shows that follistatin applied to the skin works, and no form of follistatin is an approved or proven hair-loss treatment. Follistatin injections, "research peptides" and gene therapies sold outside regulated trials are unapproved and of unknown safety.

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Clinics

1 / 4 results

Hair Loss Treatments
Surface ClinicShipley, England · GB

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