research Analysis of breast health outcomes in women on oral 5-alpha reductase inhibitors: A single-center retrospective cohort study
Oral 5-alpha reductase inhibitors do not increase breast cancer or benign breast disorder risk in women.
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5 / 1000+ resultsresearch No Increased Cardiovascular Hazard with Oral 5-Alpha-Reductase Inhibitors in Treatment of Androgenetic Alopecia: A TriNetX Retrospective Cohort Study
Oral 5-alpha-reductase inhibitors for hair loss don't increase heart risk.
research Comparative Efficacy of Oral and Topical 5-Alpha Reductase Inhibitors in Reducing Dihydrotestosterone levels across Men with Androgenetic Alopecia: A Network Meta-Analysis incorporating Post-Hoc Analyses of Randomized Clinical Trial Data
In this study, network meta-analyses were used to explore the ranking of various 5-alpha reductase inhibitor regimens on reducing dihydrotestosterone levels and to investigate whether this reduction correlates with increased total hair density in male androgenetic alopecia.
research The Effects of Oral 5-alpha Reductase Inhibitors on Penile Intracavernosal Pressures and Penile Morphology in Rat Model.
This study on rats found that finasteride and dutasteride increased collagen density in penile tissues and caused changes in prostate cells, but did not significantly alter erectile pressures compared to controls.
research Hair growth effects of oral administration of finasteride, a steroid 5 alpha-reductase inhibitor, alone and in combination with topical minoxidil in the balding stumptail macaque.
In this study, the combination of finasteride and minoxidil significantly increased hair growth in balding male stumptail macaques compared to each drug alone.
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5 / 1000+ resultscommunity Androsterone as a Neurosteroid Replacement Strategy for 5α-Reductase Inhibitor–Associated Sexual and Affective Dysfunction
Androsterone may help with sexual and affective dysfunction from finasteride by replacing disrupted neurosteroids without increasing androgenic side effects. Controlled testing is needed to confirm its effectiveness and safety.
community Is it safe to take oral dutasteride with pyrilutamide?
It's safe to take oral dutasteride with pyrilutamide, as many use 5-alpha-reductase inhibitors with topical antiandrogens for better results. Avoid ingesting pyrilutamide.
community Is there any role for topical DHT antagonists, or does a 5-AR inhibitor remove the need for them as therapy
Topical androgen receptor antagonists may not be necessary if 5-AR inhibitors like finasteride or dutasteride effectively reduce DHT levels. Combining a 5-AR inhibitor with a topical androgen antagonist could potentially enhance treatment, but oral use of androgen antagonists is too risky due to severe side effects.
community Experiences starting with finasteride vs dutasteride in your early 20s? (Gym performance & long-term results)
A 24-year-old male plans to treat male pattern hair loss with oral minoxidil and a 5-alpha-reductase inhibitor, seeking advice on finasteride versus dutasteride. Users share experiences, noting good results with finasteride and minoxidil, with some concerns about potential shedding when switching to dutasteride.
community We need actual hair loss studies on Epristeride
Epristeride is a selective 5 alpha reductase type 2 inhibitor that may reduce scalp DHT similarly to finasteride, with potentially fewer side effects. It is suggested that combining epristeride with finasteride or dutasteride could enhance hair loss treatment effectiveness.
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6 / 9 results- How is Fluridil different from other DHT blockers like finasteride? Fluridil is a topical androgen-receptor blocker applied to the scalp, while finasteride is an oral 5-alpha-reductase inhibitor that lowers DHT throughout the body. Finasteride is FDA-approved and far better studied; Fluridil rests on one 43-man trial and is not licensed as a hair-loss medicine, so its long-term safety and effect size are unknown.
learn Fluridil
learn Finasteride
Frontline, gold standard treatment for combatting androgenic alopecia
learn Dutasteride
Heavy duty finasteride that comes with higher risks
learn Overview
learn Neem Oil
natural substance from Neem tree with medicinal and pesticidal properties
learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
Clinics
6 / 11 results- 20
Hair TransplantMinnesota Oral & Facial SurgeryMinneapolis, MN · US - 30
Hair TransplantKansas City Facial & Oral SurgeryLee's Summit, MO · US - 37
Hair Loss TreatmentsOra RegénévaSaguenay, QC · CA - 42
Hair TransplantHair Loss TreatmentsDermatologyORA Skin ClinicsHyderabad, Telangana · IN - 30
Hair Loss TreatmentsOra BeautyVaughan, ON · CA - 14
Hair Loss TreatmentsOpal Aesthetic & Trichology ClinicRajkot, Gujarat · IN
Experts
6 / 16 results- 14SMP Specialist
Opal
Incomplete name
Cedar Park, TX, United States
- 68
Hair Transplant SurgeonDr. Nükhet Önal-Taylan
Düsseldorf, Nordrhein-Westfalen, Germany
- 27
DermatologistDr. Arlha Aporia Debinta, MD, Sp.D.V.E.
Jakarta, Indonesia
- 35Hair Loss Specialist
Earl True Anderson -Blake
Savannah, GA, United States
- 61
Hair Transplant SurgeonDr. Ariel Cotignola
Barcelona, Catalunya, Spain
- 3
Hair Transplant SurgeonDr. Aurélie Mercurelli
Antibes, France