The Trichoscopy Derived Sinclair Scale: Enhancing Visual Assessment Through Quantitative Trichoscopy

The study introduced the Trichoscopy Derived Sinclair Scale, a quantitative method to assess hair midline density in patients with androgenetic alopecia (AGA), and compared it to the traditional visual Sinclair Scale. A total of 380 patients (290 female and 90 male) with different stages of AGA were evaluated using both methods. The study found a very good correlation between the visual Sinclair Scale and a novel trichoscopy parameter called cumulative hair thickness density (CHTD). The Trichoscopy Derived Sinclair Scale was calculated using the formula: 3.9 × log(1/CHTD) + 2.4. This new scale was found to be more objective and reproducible than the visual assessment, with over 75% of cases showing less than one point difference between the two scales. The study concluded that the Trichoscopy Derived Sinclair Scale could be used interchangeably with the visual Sinclair Scale, offering a more accurate and reliable method for evaluating hair loss severity in AGA patients.