TLDR Dupilumab may help regrow hair in people with atopic dermatitis.
A case report from 2019 documented that dupilumab, a medication typically used for atopic dermatitis, also improved alopecia areata in a patient. This suggests that dupilumab, which targets IL-4 and IL-13 pathways, might have potential benefits for treating alopecia areata in patients with concurrent atopic dermatitis.
77 citations
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June 2017 in “Advances in Therapy” New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.
176 citations
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August 2015 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.
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December 2006 in “Archives of dermatology” Adalimumab may cause severe hair loss in some patients.
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April 2025 in “Biologics” Dupilumab and ustekinumab are promising treatments for alopecia areata, showing significant hair regrowth.
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October 2024 in “Dermatology Practical & Conceptual” Dupilumab may worsen Alopecia Areata in some males but improve it in some females, suggesting personalized treatment is needed.
72 citations
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March 2023 in “Biomolecules” Dupilumab effectively treats various inflammatory skin diseases beyond its initial use for atopic dermatitis.
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July 2025 in “Diagnostics” Dupilumab users have a higher risk of developing alopecia areata.
September 2025 in “Frontiers in Immunology” Atopic dermatitis and alopecia areata share immune and genetic factors, and targeted therapies may help both.
