Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases
April 2018
in “
Trends in Molecular Medicine
”
Lichen Planopilaris Frontal Fibrosing Alopecia epithelial stem cells hair follicle interferon-γ peroxisome proliferator-activated receptor-γ immune privilege epithelial-mesenchymal transition PPAR-γ agonists pioglitazone cholesterol biosynthesis sex steroids genetics oxidative stress LPP FFA eSCs IFN-γ PPAR-γ IP EMT
Studysummary This review discusses the roles of interferon-γ and PPAR-γ-mediated signalling in scarring alopecia, suggesting these pathways as potential therapeutic targets, but it reports no new empirical results.
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