Frontal Fibrosing Alopecia Among Men: A Clinicopathologic Study of 7 Cases
October 2017
in “
Journal of The American Academy of Dermatology
”
TLDR Men with Frontal fibrosing alopecia typically lose hair on the front scalp and sometimes on sideburns and upper lip, with treatments showing varied success.
The document summarizes a retrospective review of 7 male patients with Frontal fibrosing alopecia (FFA) at the Mayo Clinic, revealing that FFA in men has clinical and histopathologic characteristics similar to those in women, with unique involvement of sideburns and facial hair. The study found that all patients experienced hair loss in the frontal scalp, with some also losing hair in the sideburns, temporal scalp, and on the upper cutaneous lip. Biopsies confirmed LPP in all cases, and there was no common association with autoimmune or thyroid disease, although two patients had hypogonadism. The study's findings highlight the importance of recognizing the distribution of hair loss and associated hormonal abnormalities for diagnosing FFA in men, despite the small sample size and varied follow-up. The treatments used, including hydroxychloroquine with topical clobetasol and pimecrolimus, showed variable effectiveness in slowing disease progression.
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