Frontal Fibrosing Alopecia Among Men: A Clinicopathologic Study of 7 Cases

    July 2017 in “ Journal of The American Academy of Dermatology ”
    Stanislav N. Tolkachjov, Hafsa Chaudhry, Michael Camilleri, Rochelle R. Torgerson
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    TLDR Men with Frontal fibrosing alopecia typically lose hair on the front scalp and sometimes on sideburns and upper lip, with treatments showing varied success.
    The document summarizes a retrospective review of 7 male patients with Frontal fibrosing alopecia (FFA) at the Mayo Clinic, revealing that FFA in men has clinical and histopathologic characteristics similar to those in women, with unique involvement of sideburns and facial hair. The study found that all patients experienced hair loss in the frontal scalp, with some also losing hair in the sideburns, temporal scalp, and on the upper cutaneous lip. Biopsies confirmed LPP in all cases, and there was no common association with autoimmune or thyroid disease, although two patients had hypogonadism. The study's findings highlight the importance of recognizing the distribution of hair loss and associated hormonal abnormalities for diagnosing FFA in men, despite the small sample size and varied follow-up. The treatments used, including hydroxychloroquine with topical clobetasol and pimecrolimus, showed variable effectiveness in slowing disease progression.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 6 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community 9 months on Fin - no progress , should I get on Dutasteride?

      in Chat  10 upvotes 4 months ago
      The user has been using finasteride, minoxidil, and nizoral for hair loss but hasn't seen regrowth, only maintenance. They are considering switching to dutasteride, which is believed to be more effective, but are concerned about potential side effects.

      community M18 - 7 Months on topical fin + min Not working for me

      in Finasteride/Dutasteride  90 upvotes 5 days ago
      Topical finasteride and minoxidil are not effective for the user, who is considering switching to oral treatments like finasteride or dutasteride. Many suggest oral medications are more effective, and some recommend additional treatments like microneedling and other topical solutions.

      community Testosterone and hair loss seeming irrelevance

      in Research/Science  81 upvotes 1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

      community Diffuse thinning is so brutal.

      in Styling  72 upvotes 1 year ago
      A 25-year-old with AGA experienced hair thinning and dandruff, stabilized with topical finasteride and minoxidil but saw minimal regrowth. They seek advice on styling and consider oral minoxidil and microneedling for denser hair.

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