Postmenopausal Frontal Fibrosing Alopecia

    January 2003 in “ Clinical and experimental dermatology ”
    Elena Naz, Carmen Vidaurrázaga, Natalia Hernández‐Cano, Pedro Herranz Pinto, Matías Mayor, Marcos Hervella, Mariano Casado
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    TLDR Postmenopausal frontal fibrosing alopecia is a type of hair loss in postmenopausal women that may stop on its own but has no effective treatment.
    Postmenopausal frontal fibrosing alopecia (PFFA) was identified as a distinct subtype of scarring alopecia affecting postmenopausal women, characterized by progressive frontal hairline recession and scarring. The study examined four women, two of whom had undergone bilateral oophorectomy, revealing a potential new association. All patients exhibited frontoparietal hairline recession, with two also experiencing eyebrow loss. Histological analysis showed perifollicular fibrosis and lymphocytic inflammation around the follicles. Despite various treatments, no effective therapy emerged, but the condition appeared self-limiting. The findings suggested that PFFA is a localized clinical variant of lichen planopilaris.
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