Postmenopausal Frontal Fibrosing Alopecia

    January 2003 in “ Clinical and experimental dermatology ”
    Elena Naz, Carmen Vidaurrázaga, Natalia Hernández‐Cano, Pedro Herranz Pinto, Matías Mayor, Marcos Hervella, Mariano Casado
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    TLDR Postmenopausal frontal fibrosing alopecia is a type of hair loss in postmenopausal women that may stop on its own but has no effective treatment.
    Postmenopausal frontal fibrosing alopecia (PFFA) was identified as a distinct subtype of scarring alopecia affecting postmenopausal women, characterized by progressive frontal hairline recession and scarring. The study examined four women, two of whom had undergone bilateral oophorectomy, revealing a potential new association. All patients exhibited frontoparietal hairline recession, with two also experiencing eyebrow loss. Histological analysis showed perifollicular fibrosis and lymphocytic inflammation around the follicles. Despite various treatments, no effective therapy emerged, but the condition appeared self-limiting. The findings suggested that PFFA is a localized clinical variant of lichen planopilaris.
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      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Diffuse thinning is so brutal.

      in Styling  72 upvotes 1 year ago
      A 25-year-old with AGA experienced hair thinning and dandruff, stabilized with topical finasteride and minoxidil but saw minimal regrowth. They seek advice on styling and consider oral minoxidil and microneedling for denser hair.

      community An updated, simple guide to the most effective hair loss treatments

       193 upvotes 5 years ago
      Effective treatments for hair loss, including Dutasteride, Finasteride, Minoxidil, Dermarolling, LLLT, PRP, Ketoconazole, and Scalp Massage. In addition, anti-inflammatory diets and stress management are recommended to maintain or regrow hair.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community 9 months progress looks good to me

      in Is this regrowth?  86 upvotes 3 months ago
      A 35-year-old male reported positive hair regrowth after 9 months using oral dutasteride 0.5mg and oral minoxidil 5mg daily. A reply emphasized the importance of commitment and consistency for hair regrowth.

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