Postmenopausal Frontal Fibrosing Alopecia

Postmenopausal frontal fibrosing alopecia (PFFA) was identified as a distinct subtype of scarring alopecia affecting postmenopausal women, characterized by progressive frontal hairline recession and scarring. The study examined four women, two of whom had undergone bilateral oophorectomy, revealing a potential new association. All patients exhibited frontoparietal hairline recession, with two also experiencing eyebrow loss. Histological analysis showed perifollicular fibrosis and lymphocytic inflammation around the follicles. Despite various treatments, no effective therapy emerged, but the condition appeared self-limiting. The findings suggested that PFFA is a localized clinical variant of lichen planopilaris.