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GlossaryLymphocytic Inflammation

immune response where lymphocytes accumulate in tissue

Lymphocytic inflammation refers to a type of immune response where lymphocytes, a kind of white blood cell, accumulate in a particular tissue. This can occur in various conditions, including autoimmune diseases and infections, where the body's immune system targets its own cells or responds to pathogens. In the context of hair loss, such as in alopecia areata, lymphocytic inflammation can target hair follicles, leading to hair loss.

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research Lymphocytic Mediated Alopecia: Histological Classification by Pattern Analysis

29 citations, March 2001 in “Clinics in Dermatology”

Steven Kossard classified lymphocyte-related hair loss into four patterns, each linked to different types of baldness.

research Early Stage Alopecia Areata Is Associated With Inflammation in the Upper Dermis and Damage to the Hair Follicle Infundibulum

22 citations, June 2013 in “Australasian Journal of Dermatology”

Early stage bald spots are linked to skin inflammation and damage to the upper part of the hair follicle.

research Substance P in Keratosis Follicularis Spinulosa Decalvans

4 citations, September 2015 in “JAAD case reports”

Substance P may play a role in the inflammation seen in keratosis follicularis spinulosa decalvans.

Histopathological Findings of Uncomplicated Hair Transplant for Male Androgenetic Alopecia: Can Lichen Planopilaris Features Be Present?

research Histopathological Findings of Uncomplicated Hair Transplant for Male Androgenetic Alopecia: Can Lichen Planopilaris Features Be Present?

1 citations, January 2020 in “Skin appendage disorders”

Hair transplants for male baldness can show inflammation and fibrosis, but more research is needed to confirm LPP presence.

research Fibrosing Alopecia in a Pattern Distribution

April 2012 in “Informa Healthcare eBooks”

Fibrosing alopecia in a pattern distribution is a unique hair loss condition with inflammation and scarring, resembling but distinct from common balding.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Lost density 60% all over scalp in 120 days (4months)

in Update 10 upvotes 5 months ago

A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 2 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.