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GlossaryLymphocytic Cicatricial Alopecia

immune system attacks hair follicles, causing permanent scarring

Lymphocytic Cicatricial Alopecia is a type of hair loss where the immune system mistakenly attacks hair follicles, leading to permanent scarring and hair loss. This condition involves lymphocytes, a type of white blood cell, which infiltrate the hair follicles and cause inflammation, eventually destroying the follicles and replacing them with scar tissue.

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research Line-Field Confocal Optical Coherence Tomography: A New Diagnostic Method of Lichen Planopilaris

1 citations, October 2023 in “Skin research and technology”

LC-OCT is an effective new method for diagnosing classic lichen planopilaris.

research Topical Gabapentin for the Treatment of Symptomatic Scalp in Cicatricial Alopecias

April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

Topical gabapentin was safe and effective for treating scalp symptoms and promoting hair regrowth in cicatricial alopecias.

research Proceedings of the 7th World Congress of Hair Research

1 citations, January 2013 in “International Journal of Trichology”

The conference discussed various hair disorders and treatments, including the use of topical steroids, high doses of cetrizine, and hair grafting, as well as the psychological impact of hair loss.

research Lymphocytic Cicatricial Alopecia: Report of Two Cases

December 2018 in “International journal of women’s dermatology”

Early diagnosis and strong corticosteroids are crucial for managing lymphocytic cicatricial alopecia.

research Clinical Features of Primary Cicatricial Alopecia in Chinese Patients

28 citations, January 2014 in “Indian Journal of Dermatology, Venereology and Leprology”

Chinese patients with primary cicatricial alopecia often have folliculitis decalvans, benefit from treatment, but may experience relapse, with dermoscopy being a useful diagnostic tool.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 6 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Dutasteride Isn't Working? Get a Scalp Biopsy NOW

in Finasteride/Dutasteride 19 upvotes 2 weeks ago

Dutasteride may not be effective for everyone due to underlying issues, suggesting scalp biopsies for further diagnosis. Users discuss using higher doses of dutasteride, topical treatments, minoxidil, and pyrilutamide for hair loss management.

community Lost density 60% all over scalp in 120 days (4months)

in Update 10 upvotes 9 months ago

A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 6 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.