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GlossaryLymphocyte Transformation Test

laboratory test measuring lymphocyte response to antigens or mitogens

The Lymphocyte Transformation Test (LTT) is a laboratory test used to assess the function of lymphocytes, a type of white blood cell involved in the immune response. By exposing lymphocytes to specific antigens or mitogens and measuring their proliferation, the test helps evaluate immune system activity and can be used to diagnose conditions like allergies, infections, or immune deficiencies.

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Positive Lymphocyte Transformation Test in a Patient with Allergic Contact Dermatitis of the Scalp After Short-Term Use of Topical Minoxidil Solution

research Positive Lymphocyte Transformation Test in a Patient with Allergic Contact Dermatitis of the Scalp After Short-Term Use of Topical Minoxidil Solution

38 citations, June 2005 in “Contact Dermatitis”

Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.

research Severe Hypersensitivity Reaction to Gold: Positive Lymphocyte Transformation Test

19 citations, August 1972 in “PubMed”

The patient had a severe allergic reaction to gold treatment.

research Hypersensitivity Reactions to Anticoagulant Drugs: Diagnosis and Management Options

130 citations, October 2006 in “Allergy”

Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.

research T Cell–Mediated Acute Localized Exanthematous Pustulosis Caused by Finasteride

25 citations, February 2012 in “The Journal of Allergy and Clinical Immunology”

Finasteride caused a rare skin rash in a man, which improved after stopping the medication.

research Propylthiouracil-Induced Alopecia Accompanying Hypohidrosis and Onychomadesis

August 2022 in “Acta dermato-venereologica”

Propylthiouracil can cause hair loss, reduced sweating, and nail issues, but stopping the drug can reverse hair and nail problems.

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community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 2 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Lost density 60% all over scalp in 120 days (4months)

in Update 10 upvotes 5 months ago

A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.