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Glossary Lymphocyte Transformation Test

laboratory test measuring lymphocyte response to antigens or mitogens

The Lymphocyte Transformation Test (LTT) is a laboratory test used to assess the function of lymphocytes, a type of white blood cell involved in the immune response. By exposing lymphocytes to specific antigens or mitogens and measuring their proliferation, the test helps evaluate immune system activity and can be used to diagnose conditions like allergies, infections, or immune deficiencies.

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Research

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Positive Lymphocyte Transformation Test in a Patient with Allergic Contact Dermatitis of the Scalp After Short-Term Use of Topical Minoxidil Solution

research Positive lymphocyte transformation test in a patient with allergic contact dermatitis of the scalp after short-term use of topical minoxidil solution

38 citations , June 2005 in “Contact Dermatitis”

This case report describes a patient with an allergic sensitization to minoxidil, indicating that such patients should pursue alternative therapies to treat androgenetic alopecia.

research Severe hypersensitivity reaction to gold. Positive lymphocyte transformation test.

19 citations , August 1972 in “PubMed”

This report suggests that a severe reaction involving dermatitis, alopecia, and fever in a patient receiving aurothioglucose was likely allergic, as indicated by clinical findings and a positive lymphocyte transformation test.

research Hypersensitivity reactions to anticoagulant drugs: diagnosis and management options

130 citations , October 2006 in “Allergy”

This review discusses hypersensitivity reactions to anticoagulants, highlighting the importance of early diagnosis and exploring various diagnostic and management options, but it presents no new clinical findings.

TCL1 Transgenic Mouse Model as a Tool for the Study of Therapeutic Targets and Microenvironment in Human B-Cell Chronic Lymphocytic Leukemia

research TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia

38 citations , January 2016 in “Cell Death and Disease”

This review discusses the role of the TCL1 transgenic mouse model in understanding chronic lymphocytic leukemia biology and highlights the importance of exploring new pathogenetic and therapeutic targets.