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GlossaryLymphocytic Infiltration

accumulation of immune cells in tissue causing inflammation

Lymphocytic infiltration refers to the accumulation of lymphocytes, a type of white blood cell, in a particular tissue or organ. This often occurs as part of the body's immune response to infection, inflammation, or autoimmune conditions, where the immune system mistakenly attacks healthy cells. In the context of hair and alopecia, lymphocytic infiltration can be seen in conditions like alopecia areata, where the immune system targets hair follicles, leading to hair loss.

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research Lymphocytic Infiltration of the Skin Jessner-Kanof After Treatment With a Hydroquinone-Containing Bleaching Cream

20 citations, December 2006 in “Archives of dermatology”

research Pulsed Dye Laser Treatment of Jessner Lymphocytic Infiltration of the Skin

February 2009 in “Journal of The American Academy of Dermatology”

Pulsed dye laser treatment was effective for a skin condition resistant to other treatments.

research Alopecia Areata with Lymphocytic Mural Folliculitis Affecting the Isthmus in a Thoroughbred Mare

14 citations, August 2004 in “Veterinary Dermatology”

The horse had a rare type of hair loss caused by immune cells attacking hair follicles.

research Lymphocytic Mural Folliculitis Resembling Epitheliotropic Lymphoma in Tigers (Panthera Tigris)

April 2018 in “Veterinary Pathology”

Tigers had a skin condition causing hair loss and inflammation, but the cause is unknown and treatment didn't work.

research Alopecia Areata: A Tissue-Specific Autoimmune Disease of the Hair Follicle

185 citations, August 2005 in “Autoimmunity Reviews”

Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Lost density 60% all over scalp in 120 days (4months)

in Update 10 upvotes 5 months ago

A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 2 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.