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    Glossary T cell infiltration

    movement of T lymphocytes into tissue, often causing inflammation

    T cell infiltration refers to the movement and accumulation of T lymphocytes (a type of white blood cell) into a specific tissue or organ. This process often occurs in response to infection, inflammation, or autoimmune conditions, where T cells target and attack perceived threats, such as pathogens or, in some cases, the body's own cells. In the context of alopecia, T cell infiltration can lead to the immune system attacking hair follicles, resulting in hair loss.

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    1. ISID1373 - Expression of programmed cell death 1 inversely correlated with the density of CD8+ T cells infiltrating hair follicles in alopecia areata 2023
    2. 1373 Expression of programmed cell death 1 inversely correlated with the density of CD8+ T cells infiltrating hair follicles in alopecia areata Journal of Investigative Dermatology · 2023
    3. Dandruff lesional scalp skin exhibits epidermal T cell infiltration and a weakened hair follicle immune privilege International Journal of Cosmetic Science · 2024
    4. Alopecia areata but not androgenetic alopecia is characterized by a restricted and oligoclonal T-cell receptor-repertoire among infiltrating lymphocytes Journal of Cutaneous Pathology · 1997 · 19 citations
    5. CD80CD86 deficiency disrupts regulatory CD4+FoxP3+T cell homoeostasis and induces autoimmune-like alopecia Experimental dermatology · 2017 · 6 citations
    6. Immunohistochemical analysis of T-cell subsets in the inflammatory infiltrates of alopecia areata and its comparison with androgenetic alopecia International Journal of Dermatology · 2020
    7. Direct T-cell effects of minoxidii Clinics in Dermatology · 1988 · 7 citations
    8. A biopsy-sized 3D skin model with a perifollicular vascular plexus enables studying immune cell trafficking in the skin Biofabrication · 2024 · 6 citations
    9. 0150 Single-cell and spatial transcriptome profiling reveals innate-adaptive crosstalk in alopecia areata Journal of Investigative Dermatology · 2025
    10. TNC+ fibroblasts involve in skin inflammation via neuro-immune and interacting with T cells Research Square (Research Square) · 2023
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    Community 6 of 780

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    4. Why did this recent research paper from professor Tsuji lab in Japan largely go unnoticed by this sub? Isn't this discovery huge? (hair cloning) Reddit · 11 May 2026
    5. Trying to understand finasteride side effects and post finasteride syndrome Reddit · 31 Oct 2020
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