Male Frontal Fibrosing Alopecia with Generalized Hair Loss

The document reports a case of a 66-year-old man with male frontal fibrosing alopecia (FFA), a condition that predominantly affects postmenopausal women and is considered a variant of lichen planopilaris (LPP). The patient presented with a receding fronto-temporal hairline and extensive loss of body hair, including the axillae, limbs, and pubic area. Histopathological examination confirmed the diagnosis of LPP. Treatment with oral prednisolone and topical clobetasol propionate foam halted the progression of hair loss, but a 6-month trial with 5% minoxidil did not stimulate significant hair regrowth. At follow-up, the patient's condition was stable, but he reported a slow relapse of the disease by October 2012, with no regrowth of lost body hair. The case highlights the rarity of FFA in men and the challenges in its treatment, emphasizing the need for more evidence to determine the effectiveness of early aggressive intervention for an optimal prognosis.