Male Frontal Fibrosing Alopecia with Generalized Hair Loss

    November 2012 in “ Australasian Journal of Dermatology ”
    WenChieh Chen, Evanthia Kigitsidou, Hanna Prucha, Johannes Ring, Christian Andrés
    Image of study
    TLDR A 66-year-old man with a rare case of male frontal fibrosing alopecia did not regrow hair despite treatment.
    The document reports a case of a 66-year-old man with male frontal fibrosing alopecia (FFA), a condition that predominantly affects postmenopausal women and is considered a variant of lichen planopilaris (LPP). The patient presented with a receding fronto-temporal hairline and extensive loss of body hair, including the axillae, limbs, and pubic area. Histopathological examination confirmed the diagnosis of LPP. Treatment with oral prednisolone and topical clobetasol propionate foam halted the progression of hair loss, but a 6-month trial with 5% minoxidil did not stimulate significant hair regrowth. At follow-up, the patient's condition was stable, but he reported a slow relapse of the disease by October 2012, with no regrowth of lost body hair. The case highlights the rarity of FFA in men and the challenges in its treatment, emphasizing the need for more evidence to determine the effectiveness of early aggressive intervention for an optimal prognosis.
    Discuss this study in the Community →

    Research cited in this study

    5 / 5 results

    Related Community Posts Join

    6 / 1000+ results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I tried salt water to stop the DHT itch

      in Treatment  60 upvotes 2 years ago
      Treating the itch associated with male pattern baldness, which is believed to be caused by DHT. Potential treatments discussed include salt water, finasteride, ketoconazole, and RU58841.

      community Finasteride not working isnt it MPB?

      in Finasteride/Dutasteride  5 upvotes 7 months ago
      A user is concerned that finasteride isn't working for their hair loss, questioning if it's due to male pattern baldness or low iron levels. They are advised to take finasteride daily and get blood work done.

      community I think I’ve finally found the reason for my hair loss

      in Chat  98 upvotes 2 weeks ago
      The user experienced hair loss since 2019 and tried finasteride, dutasteride, RU58841, and ketoconazole shampoo without success. A scalp biopsy showed scarring and inflammation from folliculitis, indicating chronic inflammation was affecting treatment effectiveness.

      community 9 months on Fin - no progress , should I get on Dutasteride?

      in Chat  10 upvotes 1 month ago
      The user has been using finasteride, minoxidil, and nizoral for hair loss but hasn't seen regrowth, only maintenance. They are considering switching to dutasteride, which is believed to be more effective, but are concerned about potential side effects.

      community Testosterone and hair loss seeming irrelevance

      in Research/Science  81 upvotes 1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

    Related Research

    6 / 6 results