Mitochondrial Function in Murine Skin Epithelium Is Crucial for Hair Follicle Morphogenesis and Epithelial-Mesenchymal Interactions

    March 2015 in “ Journal of Investigative Dermatology ”
    Jennifer E. Kloepper, Olivier Baris, Karen L. Reuter … Ralf Paus
    Studysummary Healthy mitochondria in skin cells are essential for proper hair growth and skin cell interaction in mice.
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    Research cited in this study 14

    1. Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development Science Signaling · 2013
    2. Topobiology of Human Pigmentation: P-Cadherin Selectively Stimulates Hair Follicle Melanogenesis ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2013
    3. Stress-Induced Production of Chemokines by Hair Follicles Regulates the Trafficking of Dendritic Cells in Skin Nature Immunology · 2012
    4. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011
    5. The Mesenchymal Component of Hair Follicle Neogenesis: Background, Methods, and Molecular Characterization Experimental Dermatology · 2009
    6. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    7. Human Female Hair Follicles Are a Direct, Nonclassical Target for Thyroid-Stimulating Hormone Journal of Investigative Dermatology · 2008
    8. Hair Growth Stimulatory Effect by a Combination of 5-Aminolevulinic Acid and Iron Ion International Journal of Dermatology · 2008
    9. Activation of Beta-Catenin Signaling Programs Embryonic Epidermis to Hair Follicle Fate Development · 2008
    10. Scratching the Surface of Skin Development Nature · 2007
    11. A Guide to Assessing Damage Response Pathways of the Hair Follicle: Lessons From Cyclophosphamide-Induced Alopecia in Mice Journal of Investigative Dermatology · 2005
    12. Epithelial Growth Control by Neurotrophins: Leads and Lessons from the Hair Follicle Progress in brain research · 2004
    13. Manipulation of Stem Cell Proliferation and Lineage Commitment: Visualization of Label-Retaining Cells in Wholemounts of Mouse Epidermis Development · 2003
    14. Chemotherapy-Induced Alopecia in Mice: Induction by Cyclophosphamide, Inhibition by Cyclosporine A, and Modulation by Dexamethasone PubMed · 1994

    Related research 5

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    2. Endogenous Human Skin Equivalent Promotes In Vitro Morphogenesis of Follicle-Like Structures Biomaterials · 2016
    3. Mesenchymal–Epithelial Interactions During Hair Follicle Morphogenesis and Cycling Seminars in Cell & Developmental Biology · 2012
    4. Dynamic Signals for Hair Follicle Development and Regeneration Stem Cells and Development · 2011
    5. Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010