Hair Growth Stimulatory Effect by a Combination of 5-Aminolevulinic Acid and Iron Ion

    Yuki Morokuma, Masashi Yamazaki, Takeyasu Maeda … Ryoji Tsuboi
    Studysummary This study suggests that a mixture of 5‐ALA and iron ion significantly improved hair growth in mice, comparable to minoxidil, without promoting keratinocyte or fibroblast proliferation in vitro.
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    Research cited in this study 4

    1. Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2007
    2. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    3. Minoxidil-Induced Hair Growth Is Mediated by Adenosine in Cultured Dermal Papilla Cells: Possible Involvement of Sulfonylurea Receptor 2B as a Target of Minoxidil Journal of Investigative Dermatology · 2001
    4. Minoxidil Upregulates the Expression of Vascular Endothelial Growth Factor in Human Hair Dermal Papilla Cells British Journal of Dermatology · 1998