5 citations
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July 2022 in “Orphanet journal of rare diseases”
RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.
A user experienced severe side effects, including heart issues, after taking oral minoxidil without consulting a doctor. They are now considering alternatives like dutasteride, PRP, or laser treatments for hair loss.
TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.
Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.