EMT-Inhibiting Transcription Factor Ovol2 Regulates Directional Cell Migration and Proliferation in Adult Skin Epithelia

April 2018 in “ Journal of Investigative Dermatology ”

Daniel Haensel, Pingliang Sun, Adam L. MacLean, Jin Shen, Xinyi Ma, Xiaohu Dai

Ovol2 hair follicle regeneration epithelial-to-mesenchymal transition EMT Zeb1 wound healing cell migration cell proliferation skin epithelia single-cell RNA sequencing scRNA-Seq

Studysummary This study found that the loss of transcription factor Ovol2 in epidermal and hair follicle stem cells leads to migration defects, which are partially improved by deleting the EMT-inducing Zeb1.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

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