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    GlossaryOVOL2

    gene regulating hair follicle development and differentiation

    OVOL2 is a gene that plays a crucial role in the regulation of hair follicle development and differentiation. It encodes a transcription factor that helps control the expression of other genes involved in hair growth and skin health. Mutations or dysregulation of OVOL2 can lead to hair disorders and contribute to conditions like alopecia.

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      community Progress: 0.5mg finasteride + 2.5 mg oral minoxidil

      in Progress Pictures  431 upvotes 3 years ago
      This user uses a combination of finasteride and oral minoxidil to treat hair loss, and reports that the treatment has had an impact on his growth without any major side effects. He also shares advice on how to obtain the necessary medications in certain countries.

      community Follicum releases some data from previous phase 2a trial

      in Research/Science  12 upvotes 2 years ago
      Follicum discovered that their drug FOL-005 increased hair count by 12 hairs per cm2 in patients with less than 255 hairs per cm2 and is planning a phase 2b trial. They are currently fundraising for the trial, and the drug may also be effective for women.

      community GT20029 Big Phase 2 Update Results!

      in Research/Science  51 upvotes 3 months ago
      GT20029 showed promising results for hair growth in a Phase II trial, with the 1.0% twice-weekly regimen being the most effective. Some users expressed skepticism and humor about the product's effects and market availability.

      community Does anyone know of the actual effectiveness of the DP2 inhibitors?

      in Question  5 upvotes 8 years ago
      Setipiprant and Fevipiprant are questioned for their effectiveness in hair maintenance, with skepticism due to lack of convincing results beyond vellus hair growth. The user is satisfied with Minoxidil and Finasteride but is curious about the potential of DP2 inhibitors.