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GlossaryOR2AT4

gene encoding an olfactory receptor influencing hair growth

OR2AT4 is a gene that encodes a specific type of olfactory receptor, which is typically involved in the sense of smell. Interestingly, research has shown that this receptor is also present in human hair follicles and can influence hair growth when activated by certain compounds, such as Sandalore, a synthetic sandalwood odorant. This discovery has potential implications for treating conditions like alopecia, where hair growth is impaired.

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Topical Sandalore, a Specific OR2AT4-Stimulating Odorant, Ameliorates Female Telogen Effluvium: Randomized, Double-Blinded, Placebo-Controlled Clinical Trial

research Topical Sandalore, a Specific OR2AT4-Stimulating Odorant, Ameliorates Female Telogen Effluvium: Randomized, Double-Blinded, Placebo-Controlled Clinical Trial

April 2019 in “Journal of Investigative Dermatology”

Sandalore®, a synthetic scent, improved hair loss and satisfaction in women with telogen effluvium.

STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction, Hair Follicle Regeneration, and Wound Healing

research STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction, Hair Follicle Regeneration, and Wound Healing

1 citations , August 2016 in “Journal of Investigative Dermatology”

Activating STAT5 in the skin's dermal papilla is key for starting hair growth, regenerating hair follicles, and healing wounds.

research Human Hair Follicles Can Smell: OR2AT4-Mediated Hair Growth Regulation

August 2016 in “Journal of Investigative Dermatology”

Human hair follicles have a scent receptor that can influence hair growth.

research OR2AT4 Activation by a Synthetic Odorant Stimulates Dermcidin Production in Human Hair Follicle Epithelium and Increases Follicular Resistance to Bacterial Contamination: A Novel Antimicrobial Folliculitis Therapy?

April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

A synthetic sandalwood odorant can boost antimicrobial production in hair follicles, making them more resistant to bacteria.

Topical Sandalore, a Specific OR2AT4-Stimulating Odorant, Ameliorates Telogen Effluvium: Randomized, Double-Blinded, Placebo-Controlled Trial

research Topical Sandalore, a Specific OR2AT4-Stimulating Odorant, Ameliorates Telogen Effluvium: Randomized, Double-Blinded, Placebo-Controlled Trial

September 2019 in “Journal of Investigative Dermatology”

Sandalore, a synthetic scent, was found to reduce hair loss and improve hair growth in women with hair shedding issues.

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community Sandalore: a scientific homemade approch

21 upvotes 7 years ago

The post discusses using Sandalore as a potential hair loss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.

community Sandalore experiment

18 upvotes 7 years ago

A user added sandalore to minoxidil for hair loss, observing some vellus hair growth and less scalp inflammation. Others tried sandalore with mixed results, discussing dosage and effectiveness compared to minoxidil and finasteride.