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GlossaryOR2AT4

gene encoding an olfactory receptor influencing hair growth

OR2AT4 is a gene that encodes a specific type of olfactory receptor, which is typically involved in the sense of smell. Interestingly, research has shown that this receptor is also present in human hair follicles and can influence hair growth when activated by certain compounds, such as Sandalore, a synthetic sandalwood odorant. This discovery has potential implications for treating conditions like alopecia, where hair growth is impaired.

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research OR2AT4, an Ectopic Olfactory Receptor, Suppresses Oxidative Stress-Induced Senescence in Human Keratinocytes

6 citations, November 2022 in “Antioxidants”

OR2AT4 helps reduce aging and cell damage in human skin cells.

Topical Sandalore, a Specific OR2AT4-Stimulating Odorant, Ameliorates Telogen Effluvium: Randomized, Double-Blinded, Placebo-Controlled Trial

research Topical Sandalore, a Specific OR2AT4-Stimulating Odorant, Ameliorates Telogen Effluvium: Randomized, Double-Blinded, Placebo-Controlled Trial

September 2019 in “Journal of Investigative Dermatology”

Sandalore, a synthetic scent, was found to reduce hair loss and improve hair growth in women with hair shedding issues.

research OR2AT4 Activation by a Synthetic Odorant Stimulates Dermcidin Production in Human Hair Follicle Epithelium and Increases Follicular Resistance to Bacterial Contamination: A Novel Antimicrobial Folliculitis Therapy?

April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

A synthetic sandalwood odorant can boost antimicrobial production in hair follicles, making them more resistant to bacteria.

Topical Sandalore, a Specific OR2AT4-Stimulating Odorant, Ameliorates Female Telogen Effluvium: Randomized, Double-Blinded, Placebo-Controlled Clinical Trial

research Topical Sandalore, a Specific OR2AT4-Stimulating Odorant, Ameliorates Female Telogen Effluvium: Randomized, Double-Blinded, Placebo-Controlled Clinical Trial

April 2019 in “Journal of Investigative Dermatology”

Sandalore®, a synthetic scent, improved hair loss and satisfaction in women with telogen effluvium.

research Human Hair Follicles Can Smell: OR2AT4-Mediated Hair Growth Regulation

August 2016 in “Journal of Investigative Dermatology”

Human hair follicles have a scent receptor that can influence hair growth.

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community Sandalore: a scientific homemade approch

20 upvotes 6 years ago

The post discusses using Sandalore as a potential hair loss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.