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GlossaryOlfactory Receptor

specialized protein in the nose that detects odors

An olfactory receptor (OR) is a specialized protein found in the sensory neurons of the nose that detects odor molecules. When an odor molecule binds to an olfactory receptor, it triggers a signal that is sent to the brain, allowing us to perceive and identify different smells. These receptors are part of a large family of G-protein-coupled receptors and are crucial for the sense of smell.

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research OR2AT4 Activation by a Synthetic Odorant Stimulates Dermcidin Production in Human Hair Follicle Epithelium and Increases Follicular Resistance to Bacterial Contamination: A Novel Antimicrobial Folliculitis Therapy?

April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

A synthetic sandalwood odorant can boost antimicrobial production in hair follicles, making them more resistant to bacteria.

research New Multi-Targeting Strategy in Hair Growth Promotion: In Vitro and In Vivo Studies

3 citations , May 2018 in “Italian journal of dermatology and venereology”

The lotion with N1-methylspermidine and Sandalore® effectively reduces hair loss and promotes hair growth.

research OR2AT4, an Ectopic Olfactory Receptor, Suppresses Oxidative Stress-Induced Senescence in Human Keratinocytes

6 citations , November 2022 in “Antioxidants”

OR2AT4 helps reduce aging and cell damage in human skin cells.

Exploring the Factors to Regulate Sweating by Transcriptome Analysis for Anhidrosis: Novel Role of Olfactory Receptors on Sweating via Exposing to Beta-Ionone

research Exploring the Factors to Regulate Sweating by Transcriptome Analysis for Anhidrosis: Novel Role of Olfactory Receptors on Sweating via Exposing to Beta-Ionone

April 2023 in “Journal of Investigative Dermatology”

Sweating can potentially be controlled through olfactory receptors, with β-ionone playing a key role, and responses may vary between genders.

Topical Odorant Application of the Specific Olfactory Receptor OR2AT4 Agonist, Sandalore, Improves Telogen Effluvium-Associated Parameters

research Topical Odorant Application of the Specific Olfactory Receptor OR2AT4 Agonist, Sandalore, Improves Telogen Effluvium-Associated Parameters

11 citations , July 2020 in “Journal of Cosmetic Dermatology”

Sandalore® improves hair growth and quality in people with hair loss.

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community Sandalore: a scientific homemade approch

18 upvotes 7 years ago

The post discusses using Sandalore as a potential hair loss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.

community Sandalore experiment

18 upvotes 7 years ago

A user added sandalore to minoxidil for hair loss, observing some vellus hair growth and less scalp inflammation. Others tried sandalore with mixed results, discussing dosage and effectiveness compared to minoxidil and finasteride.