TLDR Sandalore® improves hair growth and quality in people with hair loss.
The study demonstrated that the topical application of Sandalore®, an agonist of the olfactory receptor OR2AT4, significantly improved parameters associated with telogen effluvium, a form of hair loss. Participants reported decreased hair shedding, increased hair growth, stronger and denser hair, and overall better hair quality. Objective measurements confirmed these improvements, showing significant increases in hair volume, the ratio of terminal to vellus hairs, and the percentage of anagen (growth phase) hair follicles. The findings suggested that Sandalore® could be an effective treatment for telogen effluvium, highlighting the potential of olfactory receptor agonists in hair growth and hair loss treatments.
82 citations
,
September 2018 in “Nature Communications” A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
16 citations
,
February 2017 in “Dermatology and Therapy” The new visual scale is a quick and effective way to measure hair loss in women.
26 citations
,
December 2015 in “Journal of The European Academy of Dermatology and Venereology” New method measures female hair loss: Female Pattern Hair Loss Severity Index (FPHL-SI).
38 citations
,
January 2015 in “Journal of Cosmetic Dermatology” The nutritional supplement improved hair density and reduced hair loss in women with female pattern hair loss.
7 citations
,
January 2013 in “Supportive care in cancer” Hair mass index is a precise way to measure hair loss in chemotherapy patients.
13 citations
,
January 2012 in “Dermatologic surgery” The trichometer is a quick and reliable tool for measuring hair quantity.
42 citations
,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
1 citations
,
August 2022 in “JAAD case reports” Tofacitinib and oral minoxidil may help treat Sisaipho alopecia areata.
11 citations
,
September 2021 in “Skin Appendage Disorders” Hair count values should be standardized for each scalp region to evaluate hair disorders in Asians.
6 citations
,
December 2014 in “Clinical and Experimental Dermatology” Hair density and thickness decrease in all scalp areas for East Asians with AGA.
58 citations
,
September 2012 in “Dermatologic Clinics” Male pattern hair loss caused by follicular miniaturization; early diagnosis and treatment can reduce psychological burden.
24 citations
,
September 2012 in “Dermatologic Surgery” The conclusion is that normal scalp hair counts for Taiwanese people were established, showing age-related differences but not sex or scalp location differences.
6 citations
,
August 2006 in “Journal of Cutaneous Pathology” Two teenage brothers had a rare, treatment-resistant form of female-pattern hair loss with unusual scalp changes.
January 2001 in “대한피부과학회지” Horizontal sectioning helps diagnose hair loss, but Korean follicle differences matter.
