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GlossaryOlfactory Receptor

specialized protein in the nose that detects odors

An olfactory receptor (OR) is a specialized protein found in the sensory neurons of the nose that detects odor molecules. When an odor molecule binds to an olfactory receptor, it triggers a signal that is sent to the brain, allowing us to perceive and identify different smells. These receptors are part of a large family of G-protein-coupled receptors and are crucial for the sense of smell.

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research Olfactory Receptor OR2AT4 Regulates Human Hair Growth

82 citations , September 2018 in “Nature Communications”

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

Topical Odorant Application of the Specific Olfactory Receptor OR2AT4 Agonist, Sandalore, Improves Telogen Effluvium-Associated Parameters

research Topical Odorant Application of the Specific Olfactory Receptor OR2AT4 Agonist, Sandalore, Improves Telogen Effluvium-Associated Parameters

11 citations , July 2020 in “Journal of Cosmetic Dermatology”

Sandalore® improves hair growth and quality in people with hair loss.

research Targeting Olfactory Receptor OR2AT4: An Innovative Aptamer-Based Treatment for Hair Growth Promotion

June 2025 in “Molecular Therapy — Nucleic Acids”

A new treatment using a DNA aptamer can promote hair growth by targeting a specific receptor.

research OR2AT4, an Ectopic Olfactory Receptor, Suppresses Oxidative Stress-Induced Senescence in Human Keratinocytes

6 citations , November 2022 in “Antioxidants”

OR2AT4 helps reduce aging and cell damage in human skin cells.

research OR2AT4 Activation by a Synthetic Odorant Stimulates Dermcidin Production in Human Hair Follicle Epithelium and Increases Follicular Resistance to Bacterial Contamination: A Novel Antimicrobial Folliculitis Therapy?

April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

A synthetic sandalwood odorant can boost antimicrobial production in hair follicles, making them more resistant to bacteria.

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community Sandalore: a scientific homemade approch

18 upvotes 7 years ago

The post discusses using Sandalore as a potential hair loss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.