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    Glossary FOXC2

    gene involved in tissue development and hair follicle regulation

    FOXC2 is a gene that encodes a protein involved in the development and function of various tissues, including the formation of blood vessels and the regulation of fat storage. Mutations in FOXC2 can lead to conditions like lymphedema-distichiasis syndrome, which is characterized by swelling due to fluid retention and the presence of extra eyelashes. This gene also plays a role in hair follicle development and can impact hair growth and health.

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    Research 10 of 265

    1. Foxc1 reinforces quiescence in self-renewing hair follicle stem cells Science · 2016 · 142 citations
    2. Knockdown of FOXA2 Impairs Hair-Inductive Activity of Cultured Human Follicular Keratinocytes Frontiers in Cell and Developmental Biology · 2020 · 5 citations
    3. Transcription factor FOXC1 positively regulates SFRP1 expression in androgenetic alopecia Experimental Cell Research · 2021
    4. Complementary evolution of coding and noncoding sequence underlies mammalian hairlessness bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 2 citations
    5. Aging, alopecia, and stem cells Science · 2016 · 42 citations
    6. Identification of Potential Hub Genes in Alopecia Areata Experimental Dermatology · 2024 · 4 citations
    7. Finding bald spots on chromosome 20p11 Clinical Genetics · 2009 · 1 citations
    8. A Theoretical Model for the Treatment of Androgenetic Alopecia Using the STEAP3 Protein, and the Genetic Challenges of Treating AGA Health Science Reports · 2026
    9. In Silico Promoter Motif Analysis of Human Fertility-Related Genes Applied Biosciences · 2026
    10. Transcriptional Governance of Hair Follicle Stem Cell Quiescence and Niche Maintenance in Long-Term Tissue Regeneration Digital Commons - RU (Rockefeller University) · 2025
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