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    Spironolactone and XPB: An Old Drug with a New Molecular Target

    May 2020 in “ Biomolecules ”
    Ryan Gabbard, Robert R Hoopes, Michael G. Kemp
    Studysummary This review discusses spironolactone's new roles in tumor immunosurveillance, DNA repair inhibition, and viral infection suppression, highlighting its potential to extend uses beyond traditional applications, but reports no clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 7

    1. Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs Cancers · 2019
    2. Androgens in Women: Hormone-Modulating Therapies for Androgen-Mediated Cutaneous Disorders Journal of The American Academy of Dermatology · 2018
    3. Development and Optimization of Spironolactone Nanoparticles for Enhanced Dissolution Rates and Stability Aaps Pharmscitech · 2016
    4. Safety Considerations and Monitoring in Patients Treated with Systemic Medications for Acne Dermatologic Clinics · 2016
    5. Progress on the Road to Better Medical Care for Transgender Patients Current Opinion in Endocrinology, Diabetes and Obesity · 2013
    6. Hair Loss in Women: Medical and Cosmetic Approaches to Increase Scalp Hair Fullness British Journal of Dermatology · 2011
    7. Acne and Sebaceous Gland Function Clinics in dermatology · 2004