Topical Cetirizine for Treating Androgenetic Alopecia: A Systematic Review

    August 2022 in “ Journal of Cosmetic Dermatology ”
    Xi Chen, Hong-Mei Xiang, Ming Yang
    Studysummary This study found that 1% topical cetirizine may be more effective than a placebo in treating androgenetic alopecia but appears less effective than minoxidil for hair density, though potentially longer-lasting; however, more well-designed RCTs are needed to confirm these findings.
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    Research cited in this study 19

    1. Health-Related Quality of Life, Depression, and Self-Esteem in Patients With Androgenetic Alopecia JAMA Dermatology · 2021
    2. Efficacy of Cetirizine 1% Versus Minoxidil 5% Topical Solution in the Treatment of Male Alopecia: A Randomized, Single-Blind Controlled Study Journal of Pharmacy and Pharmaceutical Sciences · 2021
    3. Therapeutic Implications of Topical Cetirizine 1% in Treatment of Male Androgenetic Alopecia: A Case-Controlled Study Journal of Cosmetic Dermatology · 2021
    4. A Systematic Review of the Effect of Platelet-Rich Plasma on Androgenetic Alopecia in Women Dermatologic Therapy · 2020
    5. HMGB1 Promotes Hair Growth via the Modulation of Prostaglandin Metabolism Scientific Reports · 2019
    6. Male Pattern Baldness and Incidence of Prostate Cancer Medicine · 2018
    7. Prostaglandin D2-Mediated DP2 and AKT Signal Regulate the Activation of Androgen Receptors in Human Dermal Papilla Cells International Journal of Molecular Sciences · 2018
    8. Topical Cetirizine 1% for Treatment of Androgenetic Alopecia Dermatologic Therapy · 2017
    9. A Preliminary Study on Topical Cetirizine in the Therapeutic Management of Androgenetic Alopecia Journal of Dermatological Treatment · 2017
    10. Androgenetic Alopecia: An Update Of Treatment Options Drugs · 2016
    11. Does Prostaglandin D2 Hold the Cure to Male Pattern Baldness? Experimental Dermatology · 2014
    12. Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia Science Translational Medicine · 2012
    13. Therapeutic Hotline: Effectiveness of the Association of Cetirizine and Topical Steroids in Lichen Planus Pilaris - An Open-Label Clinical Trial Dermatologic therapy · 2010
    14. Androgenetic Alopecia: Clinical Features, Classification, and Treatments Endocrinology and Metabolism Clinics of North America · 2007
    15. Topical Use of Minoxidil in Children and Systemic Side Effects Dermatology · 2007
    16. Androgenetic Alopecia in Men Aged 40-69 Years: Prevalence and Risk Factors British Journal of Dermatology · 2003
    17. Molecular Mechanisms of Androgenetic Alopecia Experimental Gerontology · 2002
    18. Allergic Contact Dermatitis to Topical Minoxidil Solution: Etiology and Treatment Journal of The American Academy of Dermatology · 2002
    19. Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2001

    Related research 5

    1. Topical Cetirizine for Treating Androgenetic Alopecia: A Systematic Review Journal of Cosmetic Dermatology · 2022
    2. Therapeutic Implications of Topical Cetirizine 1% in Treatment of Male Androgenetic Alopecia: A Case-Controlled Study Journal of Cosmetic Dermatology · 2021
    3. Oral Minoxidil Improves Background Hair Thickness in Lichen Planopilaris Journal of The American Academy of Dermatology · 2020
    4. Sensitization to Saw Palmetto and Minoxidil in Separate Topical Extemporaneous Treatments for Androgenetic Alopecia Australasian Journal of Dermatology · 2002
    5. Topical 2% Minoxidil Solution in Male Pattern Alopecia: The Initial European Experience International Journal of Dermatology · 1988