Dermoscopic Evaluation of the Efficacy of Combination of Topical Spironolactone 5% and Minoxidil 5% Solutions in the Treatment of Androgenetic Alopecia: A Cross-Sectional Comparative Study

    August 2022 in “ Journal of Cosmetic Dermatology ”
    Amr Ammar, Ahmed R. Elshahid, Hussein M. Abdel-Dayem … Mohamed L. Elsaie
    Studysummary This study found that combining 5% topical minoxidil and 5% topical spironolactone solutions may enhance treatment efficacy for androgenetic alopecia in both men and women, with significant reductions in vellus hair.
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    Research cited in this study 16

    1. Prevalence of Alopecia and Its Contributing Factors Among Primary Healthcare Attendees in the Jazan Region, Saudi Arabia Journal of family medicine and primary care · 2021
    2. Efficacy and Safety Profile of Oral Spironolactone Use for Androgenic Alopecia: A Systematic Review PubMed · 2021
    3. Pumpkin Seed Oil vs. Minoxidil 5% Topical Foam for the Treatment of Female Pattern Hair Loss: A Randomized Comparative Trial Journal of Cosmetic Dermatology · 2021
    4. A Novel Topical Combination of Minoxidil and Spironolactone for Androgenetic Alopecia: Clinical, Histopathological, and Physicochemical Study Dermatologic Therapy · 2020
    5. Cross-Sectional Quality of Life Assessment in Patients with Androgenetic Alopecia Dermatologic Therapy · 2020
    6. Efficacy and Safety of a New 10% Topical Minoxidil Versus 5% Topical Minoxidil and Placebo in the Treatment of Male Androgenetic Alopecia: A Trichoscopic Evaluation Journal of Dermatological Treatment · 2019
    7. Quality of Life Assessment in Patients with Androgenetic Alopecia International Journal of Trichology · 2019
    8. Comparative Study Between Mesotherapy and Topical 5% Minoxidil by Dermoscopic Evaluation for Androgenic Alopecia in Males: A Randomized Controlled Trial International Journal of Trichology · 2019
    9. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    10. Frequency, Severity, and Related Factors of Androgenetic Alopecia in Dermatology Outpatient Clinic: Hospital-Based Cross-Sectional Study in Turkey Anais Brasileiros De Dermatologia · 2017
    11. Scalp Dermoscopy or Trichoscopy Current problems in dermatology · 2015
    12. Role of Genetics and Sex Steroid Hormones in Male Androgenetic Alopecia and Female Pattern Hair Loss: An Update Australasian Journal of Dermatology · 2011
    13. S1 Guideline for Diagnostic Evaluation in Androgenetic Alopecia in Men, Women, and Adolescents British Journal of Dermatology · 2010
    14. Treatment of Female Pattern Hair Loss with a Combination of Spironolactone and Minoxidil Australasian Journal of Dermatology · 2007
    15. Efficacy of 5% Minoxidil Versus Combined 5% Minoxidil and 0.01% Tretinoin for Male Pattern Hair Loss American Journal of Clinical Dermatology · 2007
    16. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002

    Related research 7

    1. A Survey of Patient Attitudes Towards Topical Minoxidil in the Treatment of Hair Loss PubMed · 2022
    2. Dermoscopic Evaluation of the Efficacy of Combination of Topical Spironolactone 5% and Minoxidil 5% Solutions in the Treatment of Androgenetic Alopecia: A Cross-Sectional Comparative Study Journal of Cosmetic Dermatology · 2022
    3. Sisaipho Alopecia Areata Treated With Tofacitinib and Oral Minoxidil JAAD case reports · 2022
    4. Disorders of Hair DeckerMed Medicine · 2013
    5. A PUVA-Turban as Therapeutical Option in the Management of Alopecia Areata Journal of the European Academy of Dermatology and Venereology · 1998
    6. Advances in Alopecia Areata and Androgenetic Alopecia PubMed · 1992
    7. Topical Minoxidil for Hair Growth in Alopecia Areata and Androgenetica Drugs · 1987