Has anyone try mixing spironolactone with minoxidil?
    5/8/2022

    From the encyclopedia
    Spironolactone →

    powerful topical and oral anti-androgen used mostly by women

    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    RU58841 →

    a potent but unapproved and potentially problematic topical anti-androgen

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💧 spironolactone (topical)
    💧 minoxidil (topical)
    💧 RU58841 (topical)
    the tone is 😐 neutral.

    Other terms

    Mixing spironolactone with minoxidil for hair loss is questioned, but concerns are raised about spironolactone's side effects, especially for men. RU58841 is suggested as a better alternative for topical use.
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      community RU58841 or topical spironolactone??

       4 upvotes 4 years ago
      The conversation is about choosing between RU58841 and topical spironolactone for hair loss treatment. The user is currently using a topical solution with minoxidil, alfatradiol, and progesterone, and is concerned about side effects and effectiveness of both RU58841 and spironolactone.

      community Has any premature balding guys actually saved and maintained their hair?

      in Chat  17 upvotes 1 year ago
      A user discusses their struggle with aggressive hair loss starting at a young age and their use of various treatments, including topical finasteride, minoxidil, dutasteride, and RU58841, without significant success. Other users share their experiences and suggest trying oral finasteride or dutasteride, topical spironolactone, and maintaining a vitamin regimen, while noting potential side effects like gynecomastia.

      community Recommendations for topical antiandrogens

      in Treatment  2 upvotes 9 months ago
      The conversation is about adding a topical anti-androgen to a hair loss treatment regimen that includes dutasteride and oral minoxidil. The user is considering topical finasteride or dutasteride, Nizoral shampoo, KX-826, and topical spironolactone, while avoiding RU58841 due to safety concerns.

      community Hairline regrowth without HT, what are my options?

       4 upvotes 1 year ago
      The user is using multiple topical treatments including Minoxidil, RU58841, and Spironolactone, along with supplements, to address hair loss and is considering starting oral Minoxidil. They plan to begin oral finasteride soon after experiencing side effects from topical dutasteride.

      community What’s next after DUT? Looking for solutions

       4 upvotes 3 months ago
      The conversation is about hair loss treatments, specifically discussing the use of dutasteride (DUT), minoxidil (Min), spironolactone, RU58841, and pyrilutamide. The user is considering increasing DUT dosage and exploring microneedling with topical treatments.

    Related Research

    6 / 6 results
      Clinical Updates in Hair

      research CLINICAL UPDATES IN HAIR

      19 citations , January 1997 in “Dermatologic Clinics”
      This chapter reviews various antiandrogens and androgen inhibitors, detailing their mechanisms, uses, and side effects, with a focus on spironolactone, finasteride, dutasteride, and oral contraceptives.
      Antiandrogens and Androgen Inhibitors in Dermatologic Treatments

      research Antiandrogens and Androgen Inhibitors

      November 2020 in “Elsevier eBooks”
      This source outlines various antiandrogen and androgen inhibitor drugs used to treat cutaneous disorders of hyperandrogenism, detailing their mechanisms, uses, dosages, and side effects, with emphasis on spironolactone, finasteride, dutasteride, and oral contraceptives.
      Androgenetic Alopecia: Causes, Diagnosis, and Treatment Options

      research Androgenetic alopecia

      22 citations , May 1999 in “International Journal of Dermatology”
      This article discusses androgenetic alopecia and reports no new clinical results.
      Compounding as a Current Therapeutic Option in Dermatology

      research Compounding as a Current Therapeutic Option in Dermatology

      1 citations , October 2013 in “Actas Dermo-Sifiliográficas”
      This review discusses the current role and challenges of compounding in dermatology without presenting new research results; the authors suggest its resurgence in practice despite pharmaceutical alternatives.