What’s next after DUT? Looking for solutions
    6/11/2026

    From the encyclopedia
    Dutasteride →

    Heavy duty finasteride that comes with higher risks

    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    Spironolactone →

    powerful topical and oral anti-androgen used mostly by women

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💊 Dutasteride (oral) 0.5mg 18 months
    💧 Spironolactone (topical)
    Microneedling once a month
    the tone is 😐 neutral with losing ground results.

    Other terms

    The conversation is about hair loss treatments, specifically discussing the use of dutasteride (DUT), minoxidil (Min), spironolactone, RU58841, and pyrilutamide. The user is considering increasing DUT dosage and exploring microneedling with topical treatments.
    View this post in the Community →

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    Related Research

    6 / 6 results
      New Therapeutics in the Management of Androgenetic Alopecia

      research Nouvelles thérapeutiques dans la prise en charge de l’alopécie androgénétique

      March 2025 in “HAL (Le Centre pour la Communication Scientifique Directe)”
      This thesis investigates the underlying mechanisms and treatment options for androgenetic alopecia, highlighting the molecular roles of androgens and genetic predispositions, and evaluates current and emerging therapies, such as PROTACs and Janus Kinase inhibitors, to enhance patient management.
      Clinical Updates in Hair

      research CLINICAL UPDATES IN HAIR

      19 citations , January 1997 in “Dermatologic Clinics”
      This chapter reviews various antiandrogens and androgen inhibitors, detailing their mechanisms, uses, and side effects, with a focus on spironolactone, finasteride, dutasteride, and oral contraceptives.
      Antiandrogens and Androgen Inhibitors in Dermatologic Treatments

      research Antiandrogens and Androgen Inhibitors

      November 2020 in “Elsevier eBooks”
      This source outlines various antiandrogen and androgen inhibitor drugs used to treat cutaneous disorders of hyperandrogenism, detailing their mechanisms, uses, dosages, and side effects, with emphasis on spironolactone, finasteride, dutasteride, and oral contraceptives.
      Androgenetic Alopecia: An Update on Pathogenesis and Pharmacological Treatment

      research Androgenetic Alopecia: An Update on Pathogenesis and Pharmacological Treatment

      August 2025 in “Drug Design Development and Therapy”
      This review article examines current drugs for androgenetic alopecia, focusing on their mechanisms and clinical efficacy, noting that while finasteride and minoxidil are commonly approved treatments, new drugs targeting different pathogenic pathways have emerged, offering a broader understanding and reference for AGA treatment options.
      Androgenetic Alopecia: Pathogenetic Mechanisms and Treatment Approaches

      research Андрогенетическая алопеция: патогенетические механизмы и подходы к лечению

      January 2013 in “Российский журнал кожных и венерических болезней”
      This article reviews the pathophysiology and limited effectiveness of current treatments for androgenic alopecia, including finasteride, minoxidil, botulinum toxin A, and platelet-rich plasma, and highlights the need for new therapeutic approaches; it reports no new clinical findings.