Systemic Therapy for Patients with Androgenetic Alopecia

    I. N. Kondrakhina, A. N. Mareeva
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    TLDR Some treatments like minoxidil, finasteride, and dutasteride are effective for hair loss, but there's no agreed best treatment.
    The 2015 document reviews the literature on systemic therapy for androgenic alopecia, detailing the genetic basis of the condition and the efficacy of treatments like minoxidil, cyproterone acetate, spironolactone, flutamide, finasteride, and dutasteride. It notes that minoxidil is the only proven topical treatment, while oral contraceptives containing antiandrogens are used for women and finasteride and dutasteride are effective for men. The review highlights the need for establishing treatment indications, evaluating current therapies, and developing new ones. However, as of the document's publication, the use of antiandrogenic drugs for androgenetic alopecia was limited, with no consensus on the best treatment approach.
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