Systemic Treatment Options for Androgenic Alopecia
March 2026
in “
Lithuanian University of Health Sciences
”
Studysummary In this study, a systematic review found that for androgenetic alopecia, systemic treatments like finasteride, dutasteride, and oral minoxidil are effective at slowing progression and promoting hair regrowth, with additional antiandrogen therapy options for women.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
This review examines systemic treatment options for androgenic alopecia, highlighting the importance of dihydrotestosterone (DHT) in hair follicle miniaturization and hair thinning. The study identifies 5-alpha reductase inhibitors, such as finasteride and dutasteride, and oral minoxidil as the most effective systemic treatments for slowing disease progression and promoting hair regrowth. For women, additional antiandrogen therapy like spironolactone may be used. Systemic treatment is essential, especially when topical treatments are insufficient, as it targets the fundamental mechanisms of the disease and provides broader therapeutic effects.
