Effects of Oxytocin on the Hair Growth Ability of Dermal Papilla Cells

October 2023 in “ Scientific Reports ”

Tatsuto Kageyama, Jieun Seo, Lu Yan, Junji Fukuda

oxytocin dermal papilla cells hair growth growth factors gene expression hair follicle model hair sprouting OXT DP cells

TLDR Oxytocin may help hair grow by increasing hair growth-related genes and factors.

The study "Effects of oxytocin on the hair growth ability of dermal papilla cells" explored the role of oxytocin (OXT) in hair growth. The researchers found that OXT stimulates dermal papilla (DP) cells, which are essential for hair growth, to secrete growth factors. The study used an in vitro hair growth model, treating DP cells with varying concentrations of OXT. The results indicated that while OXT treatment did not significantly affect cell proliferation rate, it did increase the expression of genes associated with hair growth in a concentration-dependent manner. Additionally, OXT treatment led to the upregulation of genes associated with hair growth-promoting factors. In an in vitro hair follicle model, OXT treatment resulted in significantly longer hair sprouting compared to the untreated control group. The study concludes that OXT has potential as a hair growth agent, but further in vivo studies are needed to confirm these findings.

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