Effects of Oxytocin on the Hair Growth Ability of Dermal Papilla Cells

    October 2023 in “ Scientific Reports ”
    Tatsuto Kageyama, Jieun Seo, Lu Yan, Junji Fukuda
    Studysummary This study explored the effects of oxytocin on hair growth and found that it upregulated growth-promoting factors in dermal papilla cells and hair follicle organoids, suggesting potential for developing new alopecia treatments.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 28

    1. In Vitro Hair Follicle Growth Model for Drug Testing Scientific Reports · 2023
    2. Hypoxia Inducible Factor-1α Promotes Trichogenic Gene Expression in Human Dermal Papilla Cells Scientific Reports · 2023
    3. Effective And Economical Cell Therapy For Hair Regeneration Biomedicine & Pharmacotherapy · 2022
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    8. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    9. Corticosterone Inhibits GAS6 to Govern Hair Follicle Stem-Cell Quiescence Nature · 2021
    10. Hormonal Effects on Hair Follicles International journal of molecular sciences · 2020
    11. Wnt Activator CHIR99021-Stimulated Human Dermal Papilla Spheroids Contribute to Hair Follicle Formation and Production of Reconstituted Follicle-Enriched Human Skin Biochemical and Biophysical Research Communications · 2019
    12. Preparation of Hair Beads and Hair Follicle Germs for Regenerative Medicine Biomaterials · 2019
    13. Hair Growth Is Promoted by BeauTop via Expression of EGF and FGF-7 Molecular Medicine Reports · 2018
    14. Induction of Hair Follicle Dermal Papilla Cell Properties in Human Induced Pluripotent Stem Cell-Derived Multipotent LNGFR(+)THY-1(+) Mesenchymal Cells Scientific Reports · 2017
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    20. The Changes in the Hair Cycle During Gestation and the Post-Partum Period Journal of the European Academy of Dermatology and Venereology · 2013
    21. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    22. A Review of Modern Surgical Hair Restoration Techniques Journal of Cutaneous and Aesthetic Surgery · 2008
    23. Hormonal Regulation of Hair Follicles Exhibits a Biological Paradox Seminars in Cell & Developmental Biology · 2007
    24. Estrogens and Human Scalp Hair Growth: More Questions Than Answers Journal of Investigative Dermatology · 2004
    25. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    26. Finasteride Drugs · 1999
    27. Minoxidil Upregulates the Expression of Vascular Endothelial Growth Factor in Human Hair Dermal Papilla Cells British Journal of Dermatology · 1998
    28. The Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Scalp Skin Testosterone and Dihydrotestosterone Concentrations in Patients with Male Pattern Baldness The Journal of Clinical Endocrinology and Metabolism · 1994

    Related research 5

    1. Activation of Beta-Catenin Signaling in CD133-Positive Dermal Papilla Cells Drives Postnatal Hair Growth PLOS ONE · 2016
    2. Dermal Papilla-Derived Wnt Ligands Are Required for Adult Hair Follicle Growth Journal of Investigative Dermatology · 2016
    3. Blockade of S100A3 Activity Inhibits Murine Hair Growth Genetics and Molecular Research · 2015
    4. Hair Follicle Expression of 1,25-Dihydroxyvitamin D3 Receptors During the Murine Hair Cycle British Journal of Dermatology · 2006
    5. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996