Systemic Causes of Hair Loss

    May 2016 in “ Annals of Medicine
    Ruei-Zeng Lin, Lilit Garibyan, Alexa B. Kimball, Lynn A. Drake
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    TLDR The article concludes that correctly diagnosing systemic causes of hair loss requires a detailed clinical evaluation and a systematic diagnostic approach.
    The 2016 article reviewed systemic causes of hair loss, identifying seven major categories: telogen effluvium, nutrition, endocrine imbalances, drugs, infections, special diseases, and malignancy. It emphasized the importance of a thorough clinical evaluation, including history taking, examination techniques, and laboratory tests, to diagnose these causes effectively. The review also discussed the psychological impact of hair loss and the need for a methodical approach to ensure appropriate treatment and patient satisfaction. Specific causes such as nutritional deficiencies, endocrine disorders, the impact of certain medications, and infections were mentioned, along with the role of systemic conditions and malignancies in hair loss. The authors highlighted the importance of a systematic diagnostic approach, including gross examination of hair, scalp visualization, hair pluck tests, laboratory studies, and scalp biopsy, to improve the quality of life for patients experiencing hair loss.
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