Hypervitaminosis A in a Patient With Alopecia Receiving Renal Dialysis

    July 1979 in “ Archives of Dermatology
    Edward Shmunes
    TLDR Patients with renal disease may develop vitamin A toxicity even with low-dose supplements.
    A patient undergoing long-term renal dialysis experienced gradual hair loss and was found to have a serum vitamin A level of 140 μg/dL, significantly higher than the normal range of 20 to 80 μg/dL. Despite only consuming vitamin A through conventional multivitamins for about three years, the patient exhibited signs of hypervitaminosis A. This condition was attributed to chronic renal disease, which can lead to relative hypervitaminosis A, and the inability of renal dialysis to effectively remove vitamin A. The study discussed the implications of administering low-dose vitamin A supplements to patients with renal disease, considering the altered vitamin A metabolism in such conditions.
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