TLDR Accurate clinical, histological, and genetic methods are key for understanding and treating hair disorders.
The document from 2003 presents findings from a workshop on hair disorders, highlighting the importance of morphology in diagnosing various hair conditions. It includes a case study of a woman with hair loss following Blaschko's lines, treated with minoxidil, and emphasizes the need for clinical and microscopic examination of hair shafts. The normal anatomy of hair follicles and the hair growth cycle are detailed, with a focus on the differences between terminal and vellus hairs. The document reports that a 4 mm punch biopsy from normal controls showed a mean follicular count of 40 hairs, with 35 terminal and 5 vellus hairs, and that horizontally sectioned scalp biopsies have a 79% accuracy rate for diagnosing chronic diffuse telogen hair loss, which increases to 98% with triple biopsies. It also discusses the genetics of papular atrichia and the identification of mutations in the HR gene. A study on male androgenetic alopecia (AGA) involving 21 untreated subjects showed that contrast-enhanced phototrichogram (CE-PTG) is effective in detecting early hair follicle disturbances and could be a standard for other diagnostic tools. The document concludes that accurate clinical, histological, and genetic approaches are crucial for understanding and treating hair disorders.
116 citations,
September 2001 in “Journal of The American Academy of Dermatology” Hair loss occurs due to fewer papillary cells, smaller follicles, and shorter growth phases.
77 citations,
March 2001 in “Clinics in Dermatology” Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.
50 citations,
August 1999 in “Experimental dermatology” The control system for hair growth cycles is not well understood and needs more research.
83 citations,
May 1999 in “International Journal of Dermatology” Hair loss that spreads out can often fix itself or be treated by finding and handling the cause.
37 citations,
January 1997 in “Clinics in Dermatology” Hair problems are common and distressing for women, but increasing knowledge of treatments offers hope.
234 citations,
December 1996 in “Journal of The American Academy of Dermatology” Middle-aged women with chronic telogen effluvium experience increased hair shedding but usually don't get significantly thinner hair.
309 citations,
May 1993 in “Journal of The American Academy of Dermatology” Horizontal scalp biopsy sections effectively diagnose and predict MPAA, with follicular density and inflammation impacting hair regrowth.
139 citations,
July 1991 in “Journal of The American Academy of Dermatology” Understanding hair follicle anatomy helps diagnose hair disorders.
2 citations,
October 2020 in “The Journal of clinical and aesthetic dermatology” The herbal mix (Biochanin A, Acetyl tetrapeptide-3, and Ginseng Extracts) and the 3% Minoxidil solution are equally effective in treating hair loss, but the herbal mix has fewer side effects.
June 2008 in “Springer eBooks” The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."
39 citations,
April 2020 in “Clinical, Cosmetic and Investigational Dermatology” Asian hair is generally straight and thick, with unique disorders and properties, and more research is needed to understand it fully.
7 citations,
July 2019 in “Clinics in Dermatology” Hair loss can indicate or worsen with systemic diseases, and treating the underlying condition is important.
January 2017 in “Springer eBooks” The document explains various skin conditions and their treatments.
