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research Advances of Non-Ionic Surfactant Vesicles (Niosomes) and Their Application in Drug Delivery

260 citations , January 2019 in “Pharmaceutics”

This study highlights that niosomes, or non-ionic surfactant based vesicles, offer an advantageous drug delivery system due to their stability, cost-effectiveness, and ability to enhance drug bioavailability and targeting efficiency for various therapeutic agents.

research Drug Repurposing for Rare Diseases

246 citations , February 2021 in “Trends in Pharmacological Sciences”

This review discusses drug repurposing strategies for rare diseases, highlighting methodologies, achievements, and challenges, but reports no new clinical results.

research Penetration of drugs through skin, a complex rate-controlling membrane

211 citations , June 2012

This review discusses recent advances in skin penetration mechanisms, specifically focusing on the enhanced understanding of the follicular pathway and its implications for transdermal therapies, immune system targeting, and nanoparticle safety.

research Enhanced delivery of drugs into and across the skin by ethosomal carriers

182 citations , January 2000 in “Drug Development Research”

This study found that ethosomal carriers enhanced dermal and transdermal drug delivery more effectively than classic liposomes, improving delivery to deep skin layers and showing potential for treating conditions like herpes labialis and diabetes.

research Drug Repositioning: New Approaches and Future Prospects for Life-Debilitating Diseases and the COVID-19 Pandemic Outbreak

170 citations , September 2020 in “Viruses”

This review highlights that drug repositioning offers a cost-effective alternative to traditional drug discovery, especially for treating orphan and resistant diseases like COVID-19, by repurposing existing drugs such as Hydroxychloroquine and Remdesivir.

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community Drug-free hair transplant while waiting for future treatments to become available to public: stupid or good plan?

in Transplants 1 month ago

A user plans a drug-free hair transplant while waiting for future treatments like stem cell therapies, which are projected to be available between 2028 and 2030. Many users express skepticism about the availability of new treatments, suggesting that relying on them is risky and that finasteride remains the most effective option.

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learn Baricitinib

Baricitinib: How did a drug for arthritis end up helping people regrow hair from alopecia areata? Baricitinib, an arthritis drug, was FDA-approved in 2022 for adults with severe alopecia areata after trials in which about a third of patients on 4 mg regained most scalp hair. It carries an FDA boxed warning, and regrowth is usually lost when it is stopped.