Search

for
Search:

GlossaryLipophilic Drugs

dissolve in fats and easily cross cell membranes

Lipophilic drugs, also known as fat-soluble drugs, are medications that dissolve in fats, oils, and lipids rather than water. This property allows them to easily cross cell membranes, which are composed of lipid bilayers, facilitating their absorption and distribution within the body. These drugs often have longer half-lives and can accumulate in fatty tissues, potentially leading to prolonged effects or toxicity.

Related Terms

Learn

0 / 0 results

— no results

Research

5 / 851 results

Follicle-Targeted Delivery of Betamethasone and Minoxidil Co-Entrapped in Polymeric and Lipid Nanoparticles for Topical Alopecia Areata Treatment

research Follicle-Targeted Delivery of Betamethasone and Minoxidil Co-Entrapped in Polymeric and Lipid Nanoparticles for Topical Alopecia Areata Treatment

September 2023 in “Pharmaceuticals”

Tiny particles improved delivery of hair loss treatments to hair follicles, with lipid-based particles performing best.

Transfollicular Drug Delivery: Penetration of Drugs Through Human Scalp Skin and Comparison of Penetration Between Scalp and Abdominal Skins In Vitro

research Transfollicular Drug Delivery: Penetration of Drugs Through Human Scalp Skin and Comparison of Penetration Between Scalp and Abdominal Skins In Vitro

82 citations, January 2002 in “Journal of drug targeting”

Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.

research Microneedle Arrays Combined With Nanomedicine Approaches for Transdermal Delivery of Therapeutics

42 citations, January 2021 in “Journal of Clinical Medicine”

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

research Nanoemulgel: For Promising Topical and Systemic Delivery

5 citations, April 2022 in “IntechOpen eBooks”

Nanoemulgel is a better way to deliver drugs through the skin for various conditions.

research Significance of the Follicular Pathway for Dermal Substance Penetration Quantified by Laser Doppler Flowmetry

10 citations, August 2015 in “Journal of biophotonics”

Hair follicles help substances penetrate the skin faster and more effectively.

View more "lipophilic drugs" in research →

Community Join

5 / 15 results

community Out of curiosity, why are Finasteride pills formulated as small tablets, while Dutasteride pills are much larger soft gel capsules?

in Finasteride/Dutasteride 41 upvotes 2 months ago

Finasteride and Dutasteride are used for hair loss, with Dutasteride often in gel form for better bioavailability. Switching from Finasteride to Dutasteride is common, with some users combining treatments like Minoxidil for improved results.

community Real world data from Europe shows that DUT is significantly safer than FIN in long term use

in Research/Science 532 upvotes 2 months ago

Dutasteride is safer than finasteride for long-term use, with fewer sexual side effects. Users experience better hair regrowth and fewer side effects with dutasteride.

community Topical Dutasteride & Microneedling Works

in Finasteride/Dutasteride 6 upvotes 5 months ago

Topical dutasteride, especially at higher concentrations, can be effective for hair loss when combined with microneedling to enhance absorption. Users discuss the side effects of finasteride and dutasteride, with some preferring topical treatments to avoid systemic side effects.

community Soundwaves & Electricity Grows Hair? | Peptide Delivery Model.

in Research/Science 2 upvotes 6 months ago

Iontophoresis and sonophoresis can enhance drug delivery into the scalp. Combining these methods may improve the effectiveness of topical treatments like dutasteride and certain peptides.

community Topical fin and min and swallowing semen

in Finasteride/Dutasteride 118 upvotes 8 months ago

A user asked if it's safe to swallow semen from a partner using topical finasteride and minoxidil. Responses varied, but most suggested it's likely safe, with minimal risk from small amounts of finasteride in semen.

View more "lipophilic drugs" in community →