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    Advances in Hair Growth

    January 2022 in “ Faculty reviews ”
    Dmitri Wall, Nekma Meah, Nicole Fagan … Rodney Sinclair
    Studysummary This review discusses recent advances in understanding hair growth mechanisms and reviews current and emerging therapies, but it presents no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 110

    1. Association of Hair Loss With Suicidality and Psychological Adverse Events vs Finasteride Use—Reply JAMA Dermatology · 2021
    2. Safety of Low-Dose Oral Minoxidil for Hair Loss: A Multicenter Study of 1404 Patients Journal of The American Academy of Dermatology · 2021
    3. Therapeutic Implications of Topical Cetirizine 1% in Treatment of Male Androgenetic Alopecia: A Case-Controlled Study Journal of Cosmetic Dermatology · 2021
    4. Topical Finasteride for the Treatment of Male Androgenetic Alopecia and Female Pattern Hair Loss: A Review of the Current Literature Journal of Dermatological Treatment · 2020
    5. A Review of the Treatment of Male Pattern Hair Loss Expert Opinion on Pharmacotherapy · 2020
    6. Global Expression Profile and Genome Methylation Signatures in Male Patients with Androgenetic Alopecia Journal of The European Academy of Dermatology and Venereology · 2019
    7. Stromal Vascular Fraction-Enriched Platelet-Rich Plasma Therapy Reverses the Effects of Androgenetic Alopecia Journal of Cosmetic Dermatology · 2019
    8. Minoxidil 1 mg Oral Versus Minoxidil 5% Topical Solution for the Treatment of Female-Pattern Hair Loss: A Randomized Clinical Trial Journal of The American Academy of Dermatology · 2019
    9. An Important Role of Cutaneous Lymphatic Vessels in Coordinating and Promoting Anagen Hair Follicle Growth PLOS ONE · 2019
    10. Extracellular Vesicles from Activated Dermal Fibroblasts Stimulate Hair Follicle Growth Through Dermal Papilla-Secreted Norrin Stem cells · 2019
    11. Dental Derived Stem Cell Conditioned Media for Hair Growth Stimulation PLOS ONE · 2019
    12. Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia Dermatologic Surgery · 2019
    13. Finasteride for Androgenetic Alopecia Is Not Associated with Sexual Dysfunction: A Survey-Based, Single-Centre, Controlled Study Journal of The European Academy of Dermatology and Venereology · 2019
    14. Prostaglandins in Androgenetic Alopecia in 12 Men and Four Women Journal of The European Academy of Dermatology and Venereology · 2019
    15. Comparative Effectiveness of Low-Level Laser Therapy for Adult Androgenic Alopecia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Lasers in Medical Science · 2019
    16. Treatment of Male Pattern Alopecia with Platelet-Rich Plasma: A Double-Blind Controlled Study with Analysis of Platelet Number and Growth Factor Levels Journal of The American Academy of Dermatology · 2018
    17. Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature and Proposed Treatment Protocol International Journal of Women's Dermatology · 2018
    18. Low-Dose Daily Aspirin Reduces Topical Minoxidil Efficacy in Androgenetic Alopecia Patients Dermatologic Therapy · 2018
    19. Minoxidil in the Treatment of Androgenetic Alopecia Dermatologic Therapy · 2018
    20. Efficacy of Non-Surgical Treatments for Androgenetic Alopecia: A Systematic Review and Network Meta-Analysis Journal of The European Academy of Dermatology and Venereology · 2018
    21. Identifying Novel Strategies for Treating Human Hair Loss Disorders: Cyclosporine A Suppresses the Wnt Inhibitor, SFRP1, in the Dermal Papilla of Human Scalp Hair Follicles PLOS Biology · 2018
    22. Regulation of Hair Follicle Development by Exosomes Derived from Dermal Papilla Cells Biochemical and Biophysical Research Communications · 2018
    23. A Systematic Review of Topical Finasteride in the Treatment of Androgenetic Alopecia in Men and Women PubMed · 2018
    24. Trichologic Response of Platelet-Rich Plasma in Androgenetic Alopecia Is Maintained During Combination Therapy Journal of The American Academy of Dermatology · 2018
    25. Introducing Platelet-Rich Stroma: Platelet-Rich Plasma and Stromal Vascular Fraction Combined for the Treatment of Androgenetic Alopecia Aesthetic Surgery Journal · 2018
    26. Minoxidil Promotes Hair Growth Through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells International Journal of Molecular Sciences · 2018
    27. Eccrine Sweat Glands Associate With the Human Hair Follicle Within a Defined Compartment of Dermal White Adipose Tissue British Journal of Dermatology · 2018
    28. Female Pattern Hair Loss: A Pilot Study Investigating Combination Therapy with Low-Dose Oral Minoxidil and Spironolactone International Journal of Dermatology · 2017
    29. Microneedling for the Treatment of Hair Loss Journal of The European Academy of Dermatology and Venereology · 2017
    30. Prostanoids and Hair Follicles: Implications for Therapy of Hair Disorders Acta dermato-venereologica · 2017
    31. New-Generation Therapies for the Treatment of Hair Loss in Men Dermatologic Clinics · 2017
    32. Further Clinical Evidence for the Effect of IGF-1 on Hair Growth and Alopecia Skin appendage disorders · 2017
    33. Efficacy of Fractional Lasers in Treating Alopecia: A Literature Review Lasers in Medical Science · 2017
    34. A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification Skin appendage disorders · 2017
    35. Hair Follicle Growth by Stromal Vascular Fraction-Enhanced Adipose Transplantation in Baldness Stem cells and cloning · 2017
    36. A Preliminary Study on Topical Cetirizine in the Therapeutic Management of Androgenetic Alopecia Journal of Dermatological Treatment · 2017
    37. Study of Gene Expression Alteration in Male Androgenetic Alopecia: Evidence of Predominant Molecular Signaling Pathways British Journal of Dermatology · 2017
    38. Minoxidil Dose Response Study in Female Pattern Hair Loss Patients Determined to Be Non-Responders to 5% Topical Minoxidil PubMed · 2017
    39. Platelet-Rich Plasma for Androgenetic Alopecia: Does It Work? Evidence from Meta-Analysis Journal of Cosmetic Dermatology · 2017
    40. Bimatoprost for the Treatment of Eyelash, Eyebrow, and Scalp Alopecia Expert Opinion on Investigational Drugs · 2017
    41. A Mechanistic Model of Platelet-Rich Plasma Treatment for Androgenetic Alopecia Dermatologic Surgery · 2016
    42. Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia Dermatologic Surgery · 2016
    43. Advances in Understanding Hair Growth F1000Research · 2016
    44. Hunting the Genes in Male-Pattern Alopecia: How Important Are They, How Close Are We and What Will They Tell Us? Experimental Dermatology · 2016
    45. Low-Level Laser Therapy and Hair Regrowth: An Evidence-Based Review Lasers in Medical Science · 2015
    46. The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial Stem Cells Translational Medicine · 2015
    47. A Guide to Studying Human Hair Follicle Cycling In Vivo Journal of Investigative Dermatology · 2015
    48. Androgenetic Alopecia: New Insights Into the Pathogenesis and Mechanism of Hair Loss F1000Research · 2015
    49. Clinical Use of Conditioned Media of Adipose Tissue-Derived Stem Cells in Female Pattern Hair Loss: A Retrospective Case Series Study International Journal of Dermatology · 2015
    50. Promising Alternative Clinical Uses of Prostaglandin F2α Analogs: Beyond the Eyelashes Journal of The American Academy of Dermatology · 2015
    51. Therapeutic Efficacy of Autologous Platelet-Rich Plasma and Polydeoxyribonucleotide on Female Pattern Hair Loss Wound Repair and Regeneration · 2014
    52. Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type Developmental Cell · 2014
    53. Similar Response Patterns to Topical Minoxidil Foam 5% in Frontal and Vertex Scalp of Men with Androgenetic Alopecia: A Microarray Analysis British Journal of Dermatology · 2014
    54. Clinical Utility and Validity of Minoxidil Response Testing in Androgenetic Alopecia Dermatologic Therapy · 2014
    55. Platelet-Rich Plasma for Androgenetic Alopecia Dermatologic Surgery · 2014
    56. Emerging Interactions Between Skin Stem Cells and Their Niches Nature Medicine · 2014
    57. 7-Phloroeckol Promotes Hair Growth on Human Follicles In Vitro Naunyn-Schmiedeberg's Archives of Pharmacology · 2014
    58. Sulfotransferase Activity in Plucked Hair Follicles Predicts Response to Topical Minoxidil in the Treatment of Female Androgenetic Alopecia Dermatologic Therapy · 2014
    59. Destruction of the Arrector Pili Muscle and Fat Infiltration in Androgenic Alopecia British Journal of Dermatology · 2014
    60. Topical Valproic Acid Increases Hair Count in Male Patients with Androgenetic Alopecia: A Randomized, Comparative, Clinical Feasibility Study Using Phototrichogram Analysis Journal of Dermatology · 2014
    61. Efficacy and Safety of a Low-Level Laser Device in the Treatment of Male and Female Pattern Hair Loss: A Multicenter, Randomized, Sham Device-Controlled, Double-Blind Study American Journal of Clinical Dermatology · 2014
    62. Novel Enzymatic Assay Predicts Minoxidil Response in the Treatment of Androgenetic Alopecia Dermatologic Therapy · 2013
    63. Organic Causes of Erectile Dysfunction in Men Under 40 Urologia Internationalis · 2013
    64. Treatment of Eyebrow Hypotrichosis Using Bimatoprost: A Randomized, Double-Blind, Vehicle-Controlled Pilot Study Dermatologic surgery · 2013
    65. Proteomic Analysis of Balding and Non-Balding Mesenchyme-Derived Dermal Papilla Cells from Androgenetic Alopecia Patients Using Online Two-Dimensional Reversed Phase-Reversed Phase LC-MS/MS Journal of Proteomics · 2013
    66. Low-Level Light Therapy for Androgenetic Alopecia: A 24-Week, Randomized, Double-Blind, Sham Device-Controlled Multicenter Trial Dermatologic Surgery · 2013
    67. The Prostamide-Related Glaucoma Therapy, Bimatoprost, Offers a Novel Approach for Treating Scalp Alopecias The FASEB Journal · 2012
    68. Effects of Topical Application of Growth Factors Followed by Microneedle Therapy in Women with Female Pattern Hair Loss: A Pilot Study Journal of Dermatology · 2012
    69. Hair Growth-Promoting Effects of Adiponectin In Vitro Journal of Investigative Dermatology · 2012
    70. Efficacy and Safety of Bimatoprost 0.03% Versus Minoxidil 3% in Enhancement of Eyebrows: A Randomized, Double-Blind, Split-Face Comparative Study Journal of dermatology · 2012
    71. Valproic Acid Induces Hair Regeneration in Murine Model and Activates Alkaline Phosphatase Activity in Human Dermal Papilla Cells PLOS ONE · 2012
    72. Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth Dermatologic Surgery · 2012
    73. Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia Science Translational Medicine · 2012
    74. Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation Cell stem cell · 2012
    75. Topical Bimatoprost for the Treatment of Eyebrow Hypotrichosis PubMed · 2012
    76. Hair Regrowth Following a Wnt- and Follistatin-Containing Treatment: Safety and Efficacy in a First-in-Man Phase 1 Clinical Trial PubMed · 2011
    77. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011
    78. A Randomized Double-Blind Placebo-Controlled Pilot Study to Assess the Efficacy of a 24-Week Topical Treatment by Latanoprost 0.1% on Hair Growth and Pigmentation in Healthy Volunteers with Androgenetic Alopecia Journal of The American Academy of Dermatology · 2011
    79. The Effect of a 1550 Nm Fractional Erbium-Glass Laser in Female Pattern Hair Loss Journal of The European Academy of Dermatology and Venereology · 2011
    80. Finasteride, 1 Mg Daily Administration on Male Androgenetic Alopecia in Different Age Groups: 10-Year Follow-Up Dermatologic Therapy · 2011
    81. Fractional Photothermolysis Laser Treatment of Male Pattern Hair Loss Dermatologic Surgery · 2010
    82. Efficacy and Safety of Finasteride Therapy for Androgenetic Alopecia Archives of Dermatology · 2010
    83. Hair Growth and Rejuvenation: An Overview Journal of Dermatological Treatment · 2010
    84. Enhancing the Growth of Natural Eyelashes: The Mechanism of Bimatoprost-Induced Eyelash Growth Dermatologic Surgery · 2010
    85. Bimatoprost in the Treatment of Eyelash Hypotrichosis Clinical ophthalmology · 2010
    86. Characterization of an In Vivo Model for the Study of Eyelash Biology and Trichomegaly: Mouse Eyelash Morphology, Development, Growth Cycle, and Anagen Prolongation by Bimatoprost British journal of dermatology/British journal of dermatology, Supplement · 2010
    87. Hair Growth Stimulated by Conditioned Medium of Adipose-Derived Stem Cells Is Enhanced by Hypoxia: Evidence of Increased Growth Factor Secretion Biomedical research · 2010
    88. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    89. The Use of Low-Level Light for Hair Growth: Part I Journal of cosmetic and laser therapy · 2009
    90. Androgens and Hair Growth Dermatologic Therapy · 2008
    91. A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2007
    92. Human Hair Growth Enhancement In Vitro By Green Tea Epigallocatechin-3-Gallate (EGCG) Phytomedicine · 2006
    93. Prevalence of Male and Female Pattern Hair Loss in Maryborough Journal of Investigative Dermatology Symposium Proceedings · 2005
    94. Transient Activation of Beta-Catenin Signaling in Adult Mouse Epidermis Induces New Hair Follicles, Continuous Activation Maintains Tumors Development · 2004
    95. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    96. Cultured Peribulbar Dermal Sheath Cells Can Induce Hair Follicle Development and Contribute to the Dermal Sheath and Dermal Papilla Journal of Investigative Dermatology · 2003
    97. In Vivo and In Vitro Evaluation of Hair Growth Potential of Hibiscus Rosa-Sinensis Linn. Journal of Ethnopharmacology · 2003
    98. Exogen, Shedding Phase of the Hair Growth Cycle: Characterization of a Mouse Model Journal of Investigative Dermatology · 2002
    99. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    100. Prostaglandin-Induced Hair Growth Survey of Ophthalmology · 2002
    101. Long-Term Multinational Experience with Finasteride 1 mg in the Treatment of Men with Androgenetic Alopecia PubMed · 2002
    102. Changes in Hair Weight and Hair Count in Men with Androgenetic Alopecia After Treatment with Finasteride, 1 mg, Daily Journal of The American Academy of Dermatology · 2002
    103. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    104. Modeling the Dynamics of Human Hair Cycles by a Follicular Automaton Proceedings of the National Academy of Sciences · 2000
    105. Finasteride in the Treatment of Men with Frontal Male Pattern Hair Loss Journal of The American Academy of Dermatology · 1999
    106. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998
    107. Local Injection of Hepatocyte Growth Factor/Scatter Factor Alters Cyclic Growth of Murine Hair Follicles Journal of Investigative Dermatology · 1998
    108. Sulfation of Minoxidil by Multiple Human Cytosolic Sulfotransferases Chemico-Biological Interactions · 1998
    109. Finasteride The New England Journal of Medicine · 1994
    110. Minoxidil Sulfation in the Hair Follicle Skin Pharmacology and Physiology · 1994

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    5. Androgenetic Alopecia and Its Remedies: A Review Journal of drug discovery and therapeutics · 2014
    6. Disorders of Hair DeckerMed Medicine · 2013
    7. Characteristics of Korean Scalp Hair and Male Pattern Baldness Journal of The Korean Medical Association · 2013
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